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1. (WO2019033245) SHRNA OF HUMAN CLOCK GENE AND USE THEREOF
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2019/033245 International Application No.: PCT/CN2017/097428
Publication Date: 21.02.2019 International Filing Date: 14.08.2017
IPC:
C12N 15/113 (2010.01) ,A61K 48/00 (2006.01) ,A61P 25/00 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
113
Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48
Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
Applicants:
深圳市博奥康生物科技有限公司 SHENZHEN BIOCAN TECHNOLOGIES CO., LTD. [CN/CN]; 中国广东省深圳市 南山区西丽街道珠光路134号珠光创新科技园1栋509室毛吉炎 MAO, Jiyan / Room 509, Building 1 Zhuguang Innovation Park, No.134 Zhuguang Road Xilii Street, Nanshan District Shenzhen, Guangdong 518055, CN
Inventors:
毛吉炎 MAO, Jiyan; CN
Priority Data:
Title (EN) SHRNA OF HUMAN CLOCK GENE AND USE THEREOF
(FR) ARNSH DU GÈNE CLOCK HUMAIN ET UTILISATION CORRESPONDANTE
(ZH) 人 CLOCK 基因的 shRNA 及应用
Abstract:
(EN) Disclosed are an shRNA of the human CLOCK gene and the use thereof. The shRNA of the human CLOCK gene comprises a CLOCK-RNAi consisting of a sequence encoding SEQ ID NO: 1 and a sequence encoding SEQ ID NO: 2. The shRNA of the human CLOCK gene can be used in the preparation of a drug for treating a disease associated with abnormal expression of the CLOCK gene.
(FR) L'invention concerne un ARNsh du gène CLOCK humain et son utilisation. L'ARNsh du gène CLOCK humain comprend un ARNi de CLOCK constitué d'une séquence codant pour SEQ ID NO : 1 et d'une séquence codant pour SEQ ID NO : 2. L'ARNsh du gène CLOCK humain peut être utilisé dans la préparation d'un médicament destiné au traitement d'une maladie associée à une expression anormale du gène CLOCK.
(ZH) 一种人CLOCK基因的shRNA及应用,该人CLOCK基因的shRNA,包括:由编码SEQ ID NO:1所示序列和编码SEQ ID NO:2所示序列构成的CLOCK-RNAi。该人CLOCK基因的shRNA可应用于制备治疗CLOCK基因表达异常相关疾病的药物。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)