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1. (WO2019033095) IMPROVED IN VITRO TRANSCRIPTION/TRANSLATION (TXTL) SYSTEM AND USE THEREOF
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2019/033095 International Application No.: PCT/US2018/046477
Publication Date: 14.02.2019 International Filing Date: 13.08.2018
IPC:
C07K 14/195 (2006.01) ,C12N 9/12 (2006.01) ,C12P 21/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195
from bacteria
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9
Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
10
Transferases (2.)
12
transferring phosphorus containing groups, e.g. kinases (2.7)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
21
Preparation of peptides or proteins
Applicants:
SYNVITROBIO, INC. [US/US]; 953 Indiana Street San Francisco, California 94107, US
Inventors:
SUN, Zachary Z.; US
CHIAO, Abel C.; US
ROBERTSON, Dan E.; US
METZGER IV, Louis E.; US
MANSFIELD, Richard; US
TREGO, Kelly S.; US
Agent:
XIE, Fang; US
Priority Data:
62/544,22811.08.2017US
Title (EN) IMPROVED IN VITRO TRANSCRIPTION/TRANSLATION (TXTL) SYSTEM AND USE THEREOF
(FR) SYSTÈME AMÉLIORÉ DE TRANSCRIPTION/TRADUCTION (TXTL) IN VITRO ET SON UTILISATION
Abstract:
(EN) Provided herein, in one aspect, is a composition for in vitro transcription and translation, comprising: a treated cell lysate derived from one or more host cells such as bacteria, archaea, plant or animal; a plurality of supplements for gene transcription and translation; an energy recycling system for providing and recycling adenosine triphosphate (ATP); and one or more exogenous additives. Methods for making and using the same are also provided.
(FR) Selon un aspect, l'invention concerne une composition pour la transcription et la traduction in vitro, comprenant : un lysat cellulaire traité dérivé d'un ou de plusieurs cellules hôtes telles que des bactéries, des archées, une plante ou un animal ; une pluralité de suppléments pour la transcription et la traduction géniques ; un système de recyclage d'énergie pour fournir de l'adénosine triphosphate (ATP) ; et un ou plusieurs additifs exogènes. L'invention concerne également des procédés de fabrication et d'utilisation de ladite composition.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)