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1. (WO2019032915) GLYCOPEPTIDE ANALOGS OF SECRETIN FAMILY PEPTIDES
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2019/032915 International Application No.: PCT/US2018/046136
Publication Date: 14.02.2019 International Filing Date: 09.08.2018
IPC:
A61K 38/00 (2006.01) ,C07K 14/72 (2006.01) ,A61K 38/22 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
705
Receptors; Cell surface antigens; Cell surface determinants
72
for hormones
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
22
Hormones
Applicants:
ARIZONA BOARD OF REGENTS OF BEHALF OF THE UNIVERSITY OF ARIZONA [US/US]; The University of Arizona, Tech Launch Arizona Univesity Services Annex, 4th Floor P.O. Box 210300A Tucson, AZ 85721, US
Inventors:
POLT, Robin, L.; US
APOSTOL, Christopher; US
HEIEN, Michael, L.; US
LIU, Chenxi; US
Agent:
NGUYEN, Quan; US
Priority Data:
62/543,15209.08.2017US
Title (EN) GLYCOPEPTIDE ANALOGS OF SECRETIN FAMILY PEPTIDES
(FR) ANALOGUES DE GLYCOPEPTIDES DE PEPTIDES DE LA FAMILLE DES SÉCRÉTINE
Abstract:
(EN) Glycopeptide analogs of secretin family peptides, including PACAP and VIP, are described herein. These glycopeptides analogs can have neuroprotective properties and enhanced ability to cross the blood brain barrier (BBB) and/or enhanced stability. These glycosylated peptides can be used as drugs for treatment of CNS disorders, such as Parkinson's disease.
(FR) L'invention concerne des analogues de glycopeptides de peptides de la famille des sécrétine, notamment PACAP et VIP. Ces analogues de glycopeptides peuvent présenter des propriétés neuroprotectrices et une capacité améliorée à traverser la barrière hématoencéphalique (BHE) et/ou une stabilité améliorée. Ces peptides glycosylés peuvent être utilisés en tant que médicaments pour le traitement de troubles du SNC, tels que la maladie de Parkinson.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)