Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2019032862) LMP1-EXPRESSING CELLS AND METHODS OF USE THEREOF
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2019/032862 International Application No.: PCT/US2018/046060
Publication Date: 14.02.2019 International Filing Date: 09.08.2018
IPC:
A61K 39/12 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
12
Viral antigens
Applicants:
DANA-FARBER CANCER INSTITUTE, INC. [US/US]; 450 BROOKLINE AVENUE BOSTON, Massachusetts 02215, US
Inventors:
ZHANG, Baochun; US
CHOI, IL-Kyu; US
WANG, Zhe; US
Agent:
CUSTER, Andrew W.; US
COUGHLIN, Sean M.; US
WILKINS, Andrew T.; US
ANIS, Hissan; US
BARTON, Steven K.; US
CHEN, Xiaoyue (Peter); US
DECONTI, Giulio A.; US
DELANEY, Marie; US
DIZEREGA, Philip; US
LAMBRECHTS, Robert J.; US
LINK, Douglas; US
POPLIN, Alan J.; US
QUINN, Anna; US
SPELLBERG, Michael; US
STEELE, Alan; US
STONE-HULSLANDER, Judith; US
TEOFILO, Javier; US
TRINQUE, Brian C.; US
VELEMA, James H.; US
VOCK, Curtis A.; US
Priority Data:
62/543,47910.08.2017US
Title (EN) LMP1-EXPRESSING CELLS AND METHODS OF USE THEREOF
(FR) CELLULES EXPRIMANT LMP1 ET LEURS PROCÉDÉS D'UTILISATION
Abstract:
(EN) The instant disclosure provides LMP1-expressing immunogenic B cells presenting exogenous antigens. Also provided are methods of activating T cells and treating cancer and infectious diseases by vaccination or adoptive cell transfer using the immunogenic B cells. The instant disclosure further provides methods and kits for producing the immunogenic B cells.
(FR) La présente invention concerne des lymphocytes B immunogéniques exprimant LMP1et présentant des antigènes exogènes. L'invention concerne également des procédés d'activation de lymphocytes T et de traitement du cancer et de maladies infectieuses par vaccination ou transfert cellulaire adoptif à l'aide des lymphocytes B immunogènes. La présente invention concerne en outre des procédés et des trousses de production de lymphocytes B immunogènes.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)