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1. (WO2019032742) HAAH AND MMP-9 ARE COMPLEMENTARY CANCER BIOMARKERS AND PREDICTORS OF METASTASIS WHEN COMBINED
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2019/032742 International Application No.: PCT/US2018/045867
Publication Date: 14.02.2019 International Filing Date: 08.08.2018
IPC:
G01N 33/50 (2006.01) ,G01N 33/53 (2006.01) ,G01N 33/574 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
574
for cancer
Applicants:
PANACEA PHARMACEUTICALS, INC. [US/US]; 620 Professional Drive Gaithersburg, Maryland 20879, US
Inventors:
GHANBARI, Hossein; US
SEMENUK, Mark; US
Agent:
BRUKMAN, Alla; US
Priority Data:
62/544,40211.08.2017US
Title (EN) HAAH AND MMP-9 ARE COMPLEMENTARY CANCER BIOMARKERS AND PREDICTORS OF METASTASIS WHEN COMBINED
(FR) HAAH ET MMP-9 EN TANT QUE BIOMARQUEURS DU CANCER COMPLÉMENTAIRES ET QUE PRÉDICTEURS DE MÉTASTASES LORS DE LEUR COMBINAISON
Abstract:
(EN) The present disclosure relates to methods of using biomarkers as early disease and patient outcome predictors. More particularly, the present disclosure encompasses methods of predicting cancer metastasis by detecting and/or quantifying aspartyl (asparaginyl) beta hydroxylase (HAAH) and matrix metalloproteinase 9 (MMP9) in a biological sample.
(FR) La présente invention concerne des méthodes d'utilisation de biomarqueurs en tant que prédicteurs précoces de maladie et de l'évolution de l'état de santé. Plus particulièrement, la présente invention concerne des méthodes de prédiction de métastases cancéreuses par détection et/ou quantification de l'aspartyl (asparaginyl) bêta hydroxylase (HAAH) et de la métalloprotéinase matricielle 9 (MMP9) dans un échantillon biologique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)