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1. (WO2019032345) USE OF MAGNETIC CELLS TO MANIPULATE NON-MAGNETIC CELLS



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INTERNATIONAL SEARCH REPORT (ISR)
Part 1:  1  2  3  4  5  6          Part 2:  A  B  C  D  E 
International application No. Applicant's or agent's file reference
PCT/US2018/044806 N3D-009002WO
International filing date (day/month/year) (Earliest) Priority Date (day/month/year)
01 August 2018 08 August 2017
Applicant
GREINER BIO-ONE NORTH AMERICA, INC.
FOR FURTHER ACTION: See Form PCT/ISA/220 as well as, where applicable, item 5 below.
This international search report has been prepared by this International Searching Authority and is transmitted to the applicant according to Article 18. A copy is being transmitted to the International Bureau.
It is also accompanied by a copy of each prior art document cited in this report.
1. Basis of the report
a. With regard to the language, the international search was carried out on the basis of:
the international application in the language in which it was filed.
a translation of the international application into                                          which is the language of a translation furnished for the purposes of international search (Rules 12.3(a) and 23.1(b)).
b.
This international search report has been established taking into account the rectification of an obvious mistake authorized by or notified to this Authority under Rule 91 (Rule 43.6bis(a)).
c.
1. With regard to any nucleotide and/or amino acid sequence disclosed in the international application, the international search was carried out on the basis of a sequence listing:
a. forming part of the international application as filed:
in the form of an Annex C/ST.25 text file.
on paper or in the form of an image file.
b. furnished together with the international application under PCT Rule 13ter.1(a) for the purposes of international search only in the form of an Annex C/ST.25 text file.
c. furnished subsequent to the international filing date for the purposes of international search only:
in the form of an Annex C/ST.25 text file (Rule 13ter.1(a)).
on paper or in the form of an image file (Rule 13ter.1(b) and Administrative Instructions, Section 713).
2.
In addition, in the case that more than one version or copy of a sequence listing has been filed or furnished, the required statements that the information in the subsequent or additional copies is identical to that forming part of the application as filed or does not go beyond the application as filed, as appropriate, were furnished.
3.
Additional comments:
2. Certain claims were found unsearchable
3. Unity of invention is lacking
4. Title of the invention
The text is approved as submitted by the applicant.
The text has been established by this Authority to read as follows:
5. Abstract
The text is approved as submitted by the applicant.
The text has been established, according to Rule 38.2, by this Authority as it appears in Box No. IV. The applicant may, within one month from the date of mailing of this international search report, submit comments to this Authority.
6. Drawings
a.
The figure of the drawings to be published with the abstract is Figure No. ____________
as suggested by the applicant.
as selected by this Authority, because the applicant failed to suggest a figure.
as selected by this Authority, because this figure better characterizes the invention.
b.
none of the figures is to be published with the abstract.

A. CLASSIFICATION OF SUBJECT MATTER

     C12N 5/00 (2006.01)i; G01N 27/00 (2006.01)i; C07K 16/28 (2006.01)i
According to International Patent Classification (IPC) or to both national classification and IPC

B. FIELDS SEARCHED

Minimum documentation searched (classification system followed by classification symbols):
     C12N; G01N; C07K
Documentation searched other than minimum documentation to the extent that such documents are included in the fields searched:
Electronic data base consulted during the international search (name of data base and, where practicable, search terms used):
EPO-Internal, WPI Data, BIOSIS, CHEM ABS Data, EMBASE

C. DOCUMENTS CONSIDERED TO BE RELEVANT

Category* Citation of document, with indication, where appropriate, of the relevant passages Relevant to claim No.
(1)
A
MARGOLIS L B ET AL, "Magnetoliposomes: Another principle of cell sorting", 26 October 1983 (1983-10-26), Vol. 735, No. 1, page 193-195,
XP023360500
[retrieved on  1983-10-26]
1-18
(2)
A
EP 1650293 A1 (EISAI CO LTD [JP]; OCHI MITSUO [JP]) 26 April 2006 (2006-04-26)
1-18
(3)
A
WO 2013188449 A1 (NAN03D BIOSCIENCES INC [US]) 19 December 2013 (2013-12-19)
1-18
(4)
A
WO 2010036957 A1 (UNIV RICE WILLIAM M [US]; SOUZA GLAUCO R [US]; PASQUALINI RENATA [US];) 01 April 2010 (2010-04-01)
1-18
cited in the application
(5)
A
WO 2011038370 A1 (N3D BIOSCIENCES INC [US]; SOUZA GLAUCO R [US]) 31 March 2011 (2011-03-31)
1-18
cited in the application
(6)
A
GLAUCO R. SOUZA ET AL, "Three-dimensional tissue culture based on magnetic cell levitation", NATURE NANOTECHNOLOGY,Vol. 5, No. 4, 14 March 2010 (2010-03-14), page 291-296,
XP055233171
1-18
*
Special categories of cited documents:
"A"
document defining the general state of the art which is not considered to be of particular relevance
"E"
earlier application or patent but published on or after the international filing date
"L"
document which may throw doubts on priority claim(s) or which is cited to establish the publication date of another citation or other special reason (as specified)
"O"
document referring to an oral disclosure, use, exhibition or other means
"P"
document published prior to the international filing date but later than the priority date claimed
"T"
later document published after the international filing date or priority date and not in conflict with the application but cited to understand the principle or theory underlying the invention
"X"
document of particular relevance; the claimed invention cannot be considered novel or cannot be considered to involve an inventive step when the document is taken alone
"Y"
document of particular relevance; the claimed invention cannot be considered to involve an inventive step when the document is combined with one or more other such documents, such combination being obvious to a person skilled in the art
"&"
document member of the same patent family

D. INFORMATION ON PATENT FAMILY MEMBERS

Patent document cited in search report Publication date
(day/month/year)
Patent family member(s) Publication date
(day/month/year)
EP 1650293 A1
26 April 2006
AT 491781 T
CN 1742080 A
CN 101173250 A
EP 1650293 A1
EP 2182053 A1
EP 2360240 A1
ES 2358176 T3
JP 3889026 B2
JP WO2005001070 A1
KR 20050084315 A
KR 20070047849 A
US 2006264690 A1
US 2010132722 A1
WO 2005001070 A1
15 January 2011
01 March 2006
07 May 2008
26 April 2006
05 May 2010
24 August 2011
06 May 2011
07 March 2007
27 July 2006
26 August 2005
07 May 2007
23 November 2006
03 June 2010
06 January 2005
WO 2013188449 A1
19 December 2013
BR 112014029505 A2
EP 2861167 A1
JP 2015521470 A
US 2015110752 A1
US 2018000936 A1
WO 2013188449 A1
15 May 2018
22 April 2015
30 July 2015
23 April 2015
04 January 2018
19 December 2013
WO 2010036957 A1
01 April 2010
BR PI0919036 A2
EP 2342338 A1
JP 5775455 B2
JP 2012503492 A
US 2011286975 A1
US 2014322784 A1
US 2018265858 A1
WO 2010036957 A1
21 November 2017
13 July 2011
09 September 2015
09 February 2012
24 November 2011
30 October 2014
20 September 2018
01 April 2010
WO 2011038370 A1
31 March 2011
BR 112012006558 A2
EP 2480343 A1
ES 2657242 T3
JP 5769717 B2
JP 2013505728 A
US 2012171744 A1
US 2015104844 A1
WO 2011038370 A1
26 April 2016
01 August 2012
02 March 2018
26 August 2015
21 February 2013
05 July 2012
16 April 2015
31 March 2011
Name and mailing address of the ISA/:
European Patent Office
P.B. 5818, Patentlaan 2, 2280 HV Rijswijk,
Netherlands
Telephone No. (+31-70)340-2040
Facsimile No. (+31-70)340-3016
Date of the actual completion of the international search:
08 January 2019
Date of mailing of the international search report:
17 January 2019
Authorized officer:
Armandola, Elena
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