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1. (WO2019032046) A COMPOSITION FOR TREATING AND/OR PREVENTING HEPATITIS B VIRUS INFECTION AND THE USE THEREOF
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2019/032046 International Application No.: PCT/SG2018/050391
Publication Date: 14.02.2019 International Filing Date: 01.08.2018
IPC:
A61K 39/29 (2006.01) ,A61K 39/39 (2006.01) ,A61P 37/04 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
12
Viral antigens
29
Hepatitis virus
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
39
characterised by the immunostimulating additives, e.g. chemical adjuvants
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
02
Immunomodulators
04
Immunostimulants
Applicants:
YISHENG BIOPHARMA (SINGAPORE) PTE LTD [SG/SG]; Serangoon Central Post Office, PO Box 584 Singapore 915503, SG
Inventors:
ZHANG, Yi; CN
Agent:
CHUNG, Jing Yeng; SG
Priority Data:
10201706540X10.08.2017SG
Title (EN) A COMPOSITION FOR TREATING AND/OR PREVENTING HEPATITIS B VIRUS INFECTION AND THE USE THEREOF
(FR) COMPOSITION POUR TRAITER ET/OU PRÉVENIR UNE INFECTION PAR LE VIRUS DE L'HÉPATITE B ET SON UTILISATION
Abstract:
(EN) A composition for treating and/or preventing Hepatitis B virus infection and Hepatitis B virus infection mediated diseases and the method thereof are provided. In some embodiments, the composition includes a polyriboinosinic acid-polyribocytidylic acid (PIC), at least one antibiotic or polyamide compound, at least one positive ion, and Hepatitis B virus surface antigen. In some embodiments, the composition includes PIC, at least one antibiotic or polyamide compound, at least one positive ion, Hepatitis B virus surface antigen and Hepatitis B virus core antigen. The present disclosure also relates to a method of treating and/or preventing Hepatitis B virus infection, particularly for treating chronic HBV infection.
(FR) L'invention concerne une composition pour traiter et/ou prévenir une infection par le virus de l'hépatite B et des maladies médiées par l'infection par le virus de l'hépatite B et son procédé. Dans certains modes de réalisation, la composition comprend un acide polyriboinosinique- polyribocytidylique (PIC), au moins un composé antibiotique ou polyamide, au moins un ion positif et un antigène de surface du virus de l'hépatite B. Dans certains modes de réalisation, la composition comprend un PIC, au moins un composé antibiotique ou polyamide, au moins un ion positif, un antigène de surface du virus de l'hépatite B et un antigène de surface du virus de l'hépatite B. La présente invention concerne également une méthode de traitement et/ou de prévention d'une infection par le virus de l'hépatite B, en particulier pour le traitement d'une infection chronique par le VHB.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)