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1. (WO2019032027) CHOLESTYRAMINE PELLETS, ORAL CHOLESTYRAMINE FORMULATIONS AND USE THEREOF
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2019/032027 International Application No.: PCT/SE2018/050803
Publication Date: 14.02.2019 International Filing Date: 09.08.2018
IPC:
A61K 9/16 (2006.01) ,A61K 9/50 (2006.01) ,A61K 31/785 (2006.01) ,A61P 1/00 (2006.01) ,A61P 1/12 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
16
Agglomerates; Granulates; Microbeadlets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
48
Preparations in capsules, e.g. of gelatin, of chocolate
50
Microcapsules
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
74
Synthetic polymeric materials
785
Polymers containing nitrogen
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1
Drugs for disorders of the alimentary tract or the digestive system
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1
Drugs for disorders of the alimentary tract or the digestive system
12
Antidiarrhoeals
Applicants:
ALBIREO AB [SE/SE]; Arvid Wallgrens backe 20 413 46 Göteborg, SE
Inventors:
GILLBERG, Per-Göran; SE
GUSTAFSSON, Nils Ove; SE
LÖVGREN, Kurt; SE
Agent:
NOVITAS PATENT AB; P.O.Box 55557 102 04 Stockholm, SE
Priority Data:
1750977-909.08.2017SE
Title (EN) CHOLESTYRAMINE PELLETS, ORAL CHOLESTYRAMINE FORMULATIONS AND USE THEREOF
(FR) PASTILLES DE CHOLESTYRAMINE, FORMULATIONS ORALES DE CHOLESTYRAMINE ET LEUR UTILISATION
Abstract:
(EN) The invention relates to small pellets comprising cholestyramine. The pellets have a high cholestyramine content and are stable enough to be coated with one or more coating layers. The invention also relates to amultiparticulate drug delivery system comprising such pellets.The invention further relates to an oral formulation for targeted delivery of cholestyramine to the colon, comprising a plurality of cholestyramine pellets that are coated with a colon releasecoating. The invention also relates to the use of this formulation in the treatment of bile acid malabsorption and bile acid diarrhoea.
(FR) L'invention concerne de petites pastilles comprenant de la cholestyramine. Les pastilles ont une teneur élevée en cholestyramine et sont suffisamment stables pour être revêtues d'une ou plusieurs couches de revêtement. L'invention concerne aussi un système d'administration de médicament multiparticulaire comprenant de telles pastilles. L'invention concerne en outre une formulation orale pour l'administration ciblée de cholestyramine au côlon comprenant une pluralité de pastilles de cholestyramine qui sont revêtues d'un revêtement de libération dans le côlon. L’invention concerne également l’utilisation de cette formulation dans le traitement de la malabsorption des acides biliaires et de la diarrhée causée par les acides biliaires.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)