Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2019031898) PHARMACEUTICAL COMPOSITION AND METHOD FOR PREPARING SAME
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2019/031898 International Application No.: PCT/KR2018/009142
Publication Date: 14.02.2019 International Filing Date: 09.08.2018
IPC:
A61K 9/16 (2006.01) ,A61K 9/50 (2006.01) ,A61K 9/24 (2006.01) ,A61K 9/48 (2006.01) ,A61K 31/52 (2006.01) ,A61K 31/714 (2006.01) ,A61K 31/205 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
16
Agglomerates; Granulates; Microbeadlets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
48
Preparations in capsules, e.g. of gelatin, of chocolate
50
Microcapsules
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
22
Sustained or differential release type
24
Layered or laminated unitary dosage forms
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
48
Preparations in capsules, e.g. of gelatin, of chocolate
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519
ortho- or peri-condensed with heterocyclic rings
52
Purines, e.g. adenine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7135
Compounds containing heavy metals
714
Cobalamins, e.g. cyanocobalamin, vitamin B12
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
205
Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
Applicants:
주식회사 셀트리온제약 CELLTRION PHARM, INC. [KR/KR]; 충청북도 청주시 청원구 오창읍 2산단로 82 82, 2sandan-ro, Ochang-eup, Cheongwon-gu, Cheongju-si, Chungcheongbuk-do 28117, KR
Inventors:
이병훈 LEE, Byung Hoon; KR
한은지 HAN, Eun Ji; KR
권시안 GWON, Si An; KR
박단비 PARK, Dan Bi; KR
윤소라 YUN, So Ra; KR
서은주 SEO, Eun Joo; KR
남동연 NAM, Dong Yeon; KR
오동준 OH, Dong Joon; KR
문병관 MOON, Byung Kwan; KR
박영준 PARK, Young Jun; KR
Priority Data:
10-2017-010194910.08.2017KR
Title (EN) PHARMACEUTICAL COMPOSITION AND METHOD FOR PREPARING SAME
(FR) COMPOSITION PHARMACEUTIQUE ET SA MÉTHODE DE PRÉPARATION
(KO) 약학 조성물 및 이의 제조방법
Abstract:
(EN) A pharmaceutical composition according to the present invention contains adenine, carnitine, and cyanocobalamin, and the present invention provides: a pharmaceutical composition capable of ensuring stability of adenine by using a blocker or a blocking structure; and a method for preparing the same. The pharmaceutical composition according to the present invention ensures stability of adenine, so that the content of adenine is maintained at 95% or more after six months in a stability test under acceleration conditions (40±2°C/75±5%RH).
(FR) L'invention concerne une composition pharmaceutique contenant de l'adénine, de la carnitine et de la cyanocobalamine, et la présente invention permet d'obtenir : une composition pharmaceutique susceptible d'assurer la stabilité de l'adénine à l'aide d'un bloqueur ou d'une structure de blocage; et sa méthode de préparation. La composition pharmaceutique selon la présente invention assure la stabilité de l'adénine, de telle sorte que la teneur en adénine soit maintenue à 95 % ou plus après six mois dans un test de stabilité dans des conditions d'accélération (40±2 °C/75±5 % d'humidité relative).
(KO) 본 발명에 따른 약학 조성물은 아데닌, 카르니틴 및 시아노코발라민을 포함하며, 차단제 또는 차단구조를 사용하여 아데닌의 안정성을 확보할 수 있는 약학 조성물 및 이의 제조방법을 제공한다. 본 발명에 따른 약학 조성물은 아데닌의 안정성을 확보하여 가속조건(40±2℃/75±5%RH)의 안정성시험에서 6개월 후 아데닌의 함량이 95% 이상으로 유지된다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)