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1. (WO2019031729) USE OF COMPOSITION COMPRISING STEM CELL-DERIVED EXOSOME AS EFFECTIVE INGREDIENT IN ALLEVIATING NON-ALCOHOLIC SIMPLE STEATOSIS OR NON-ALCOHOLIC STEATOHEPATITIS
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2019/031729 International Application No.: PCT/KR2018/008325
Publication Date: 14.02.2019 International Filing Date: 24.07.2018
IPC:
A61K 35/28 (2006.01) ,A61K 35/51 (2015.01) ,A61K 9/00 (2006.01) ,A23L 33/10 (2016.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
12
Materials from mammals or birds
28
Marrow; Spleen
[IPC code unknown for A61K 35/51]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
[IPC code unknown for A23L 33/10]
Applicants:
주식회사 엑소코바이오 EXOCOBIO INC. [KR/KR]; 서울시 금천구 가산디지털1로 19, 306호 Suite 306, 19, Gasan digital 1-ro Geumcheon-gu Seoul 08594, KR
Inventors:
이용원 YI, Yong Weon; KR
조병성 CHO, Byong Seung; KR
Agent:
이동기 LEE, Dong-Ki; KR
Priority Data:
10-2017-009932805.08.2017KR
10-2017-016255530.11.2017KR
Title (EN) USE OF COMPOSITION COMPRISING STEM CELL-DERIVED EXOSOME AS EFFECTIVE INGREDIENT IN ALLEVIATING NON-ALCOHOLIC SIMPLE STEATOSIS OR NON-ALCOHOLIC STEATOHEPATITIS
(FR) UTILISATION D'UNE COMPOSITION COMPRENANT UN EXOSOME DÉRIVÉ D'UNE CELLULE SOUCHE DEJA TITRE DEE PRINCIPE ACTIF POUR SOULAGER UNE STÉATOSE NON ALCOOLIQUE SIMPLE OU UNE STÉATOHÉPATITE NON ALCOOLIQUE
(KO) 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 조성물의 비알콜성 단순 지방간 또는 비알콜성 지방간염의 개선 용도
Abstract:
(EN) The present invention provides a composition comprising a stem cell-derived exosome as an effective ingredient for preventing, relieving, alleviating, or treating non-alcoholic simple steatosis or non-alcoholic steatohepatitis. A composition of the present invention can prevent, relieve, alleviate, or treat non-alcoholic simple steatosis or non-alcoholic steatohepatitis by reducing or relieving fat accumulation or inflammation in hepatocytes or liver tissues, which acts as a cause of non-alcoholic simple steatosis or non-alcoholic steatohepatitis and by inducing the histological state of non-alcoholic simple steatosis or non-alcoholic steatohepatitis to moderate, improve, or change for the better.
(FR) La présente invention concerne une composition contenant un exosome dérivé d'une cellule souche à titre de principe actif pour prévenir, atténuer ou traiter une stéatose non alcoolique simple ou une stéatohépatite non alcoolique. La composition selon la présente invention peut prévenir, atténuer, soulager ou traiter une stéatose non alcoolique simple ou une stéatohépatite non alcoolique par réduction ou atténuation de l'accumulation de graisses ou de l'inflammation dans les hépatocytes ou tissus hépatiques, qui est une des causes de la stéatose non alcoolique simple ou de la stéatohépatite non alcoolique et par induction d'une modération, amélioration, ou d'un changement pour le meilleur de l'état histologique de la stéatose non alcoolique simple ou de la stéatohépatite non alcoolique.
(KO) 본 발명은 줄기세포 유래의 엑소좀을 유효성분으로 포함하는, 비알콜성 단순 지방간 또는 비알콜성 지방간염의 예방, 완화, 개선 또는 치료용 조성물을 제공한다. 본 발명의 조성물은 비알콜성 단순 지방간 또는 비알콜성 지방간염의 원인이 되는 간 세포 또는 간 조직 내의 지방 축적 및 염증을 감소 내지는 완화시키고, 비알콜성 단순 지방간 또는 비알콜성 지방간염의 조직학적 상태도 완화, 개선 내지는 호전시켜 비알콜성 단순 지방간 또는 비알콜성 지방간염을 예방, 완화, 개선 또는 치료할 수 있다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)