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International application No. Applicant's or agent's file reference
PCT/EP2018/071796 P5343PC00
International filing date (day/month/year) (Earliest) Priority Date (day/month/year)
10 August 2018 11 August 2017
FOR FURTHER ACTION: See Form PCT/ISA/220 as well as, where applicable, item 5 below.
This international search report has been prepared by this International Searching Authority and is transmitted to the applicant according to Article 18. A copy is being transmitted to the International Bureau.
It is also accompanied by a copy of each prior art document cited in this report.
1. Basis of the report
a. With regard to the language, the international search was carried out on the basis of:
the international application in the language in which it was filed.
a translation of the international application into                                          which is the language of a translation furnished for the purposes of international search (Rules 12.3(a) and 23.1(b)).
This international search report has been established taking into account the rectification of an obvious mistake authorized by or notified to this Authority under Rule 91 (Rule 43.6bis(a)).
With regard to any nucleotide and/or amino acid sequence disclosed in the international application, the international search was carried out on the basis of a sequence listing:
2. Certain claims were found unsearchable
3. Unity of invention is lacking
4. Title of the invention
The text is approved as submitted by the applicant.
The text has been established by this Authority to read as follows:
5. Abstract
The text is approved as submitted by the applicant.
The text has been established, according to Rule 38.2, by this Authority as it appears in Box No. IV. The applicant may, within one month from the date of mailing of this international search report, submit comments to this Authority.
6. Drawings
The figure of the drawings to be published with the abstract is Figure No.     1l    
as suggested by the applicant.
as selected by this Authority, because the applicant failed to suggest a figure.
as selected by this Authority, because this figure better characterizes the invention.
none of the figures is to be published with the abstract.


     A61M 5/178 (2006.01)i; A61M 5/20 (2006.01)i; G02B 27/22 (2018.01)i; B42D 25/328 (2014.01)i
According to International Patent Classification (IPC) or to both national classification and IPC


Minimum documentation searched (classification system followed by classification symbols):
     A61M; G02B; B42D
Documentation searched other than minimum documentation to the extent that such documents are included in the fields searched:
Electronic data base consulted during the international search (name of data base and, where practicable, search terms used):
EPO-Internal, WPI Data


Category* Citation of document, with indication, where appropriate, of the relevant passages Relevant to claim No.
US 6995914 B1 (CONLEY KENNETH E [US] ET AL) 07 February 2006 (2006-02-07)
column 1, line 50 - column 3, line 13
WO 2016045699 A1 (ROMALTEK MEDICAL S L [ES]) 31 March 2016 (2016-03-31)
page 14, line 11 - page 16, line 9
WO 9907425 A1 (PHARMACIA & UPJOHN AB [SE]; LIPPE BARBARA [US]; HOLTE ANDERS [SE]; HIM) 18 February 1999 (1999-02-18)
page 3, line 11 - page 4, line 12
WO 2016193229 A1 (INSULCLOUD S L [ES]) 08 December 2016 (2016-12-08)
page 11, line 35 - page 12, line 15
EP 2060284 A1 (HOFFMANN LA ROCHE [CH]; ROCHE DIAGNOSTICS GMBH [DE]) 20 May 2009 (2009-05-20)
column 21 - column 28
US 2005152040 A1 (GOGGINS TIMOTHY P [US]) 14 July 2005 (2005-07-14)
paragraph [0028] - paragraph [0031]
Special categories of cited documents:
document defining the general state of the art which is not considered to be of particular relevance
earlier application or patent but published on or after the international filing date
document which may throw doubts on priority claim(s) or which is cited to establish the publication date of another citation or other special reason (as specified)
document referring to an oral disclosure, use, exhibition or other means
document published prior to the international filing date but later than the priority date claimed
later document published after the international filing date or priority date and not in conflict with the application but cited to understand the principle or theory underlying the invention
document of particular relevance; the claimed invention cannot be considered novel or cannot be considered to involve an inventive step when the document is taken alone
document of particular relevance; the claimed invention cannot be considered to involve an inventive step when the document is combined with one or more other such documents, such combination being obvious to a person skilled in the art
document member of the same patent family


Patent document cited in search report Publication date
Patent family member(s) Publication date
US 6995914 B1
07 February 2006
US 6995914 B1
US 7375891 B1
US 8236209 B1
07 February 2006
20 May 2008
07 August 2012
WO 2016045699 A1
31 March 2016
EP 3197535 A1
JP 2017527414 A
US 2017189621 A1
WO 2016045699 A1
02 August 2017
21 September 2017
06 July 2017
31 March 2016
WO 9907425 A1
18 February 1999
AT 340598 T
AU 738918 B2
BR 9811133 A
CA 2298739 A1
CN 1266373 A
DE 69836026 T2
DK 1001821 T3
EP 1001821 A1
ES 2272006 T3
HU 0004832 A2
IL 134379 A
JP 4149657 B2
JP 2001513371 A
KR 20010022678 A
NO 20000580 A
PL 338447 A1
PT 1001821 E
RU 2192894 C2
TW 396041 B
WO 9907425 A1
ZA 9806966 B
15 October 2006
27 September 2001
18 July 2000
18 February 1999
13 September 2000
15 March 2007
08 January 2007
24 May 2000
16 April 2007
28 May 2001
25 July 2005
10 September 2008
04 September 2001
26 March 2001
06 April 2000
06 November 2000
31 January 2007
20 November 2002
01 July 2000
18 February 1999
08 February 1999
WO 2016193229 A1
08 December 2016
AU 2016269688 A1
CA 2988408 A1
CN 108290007 A
EP 3304372 A1
JP 2018516151 A
US 2018147362 A1
WO 2016193229 A1
18 January 2018
08 December 2016
17 July 2018
11 April 2018
21 June 2018
31 May 2018
08 December 2016
EP 2060284 A1
20 May 2009
EP 2060284 A1
WO 2009062675 A1
20 May 2009
22 May 2009
US 2005152040 A1
14 July 2005
Name and mailing address of the ISA/:
European Patent Office
P.B. 5818, Patentlaan 2, 2280 HV Rijswijk,
Telephone No. (+31-70)340-2040
Facsimile No. (+31-70)340-3016
Date of the actual completion of the international search:
22 November 2018
Date of mailing of the international search report:
04 December 2018
Authorized officer:
Daintith, Nichola
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