Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2019029081) APPLICATION OF INTERFERON Κ IN THE PREPARATION OF ANTI ENVELOPED VIRUS DRUGS
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2019/029081 International Application No.: PCT/CN2017/116350
Publication Date: 14.02.2019 International Filing Date: 15.12.2017
IPC:
A61K 38/21 (2006.01) ,A61P 31/16 (2006.01) ,A61P 31/14 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
19
Cytokines; Lymphokines; Interferons
21
Interferons
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12
Antivirals
14
for RNA viruses
16
for influenza or rhinoviruses
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12
Antivirals
14
for RNA viruses
Applicants:
上海市公共卫生临床中心 SHANGHAI PUBLIC HEALTH CLINICAL CENTER [CN/CN]; 中国上海市 金山区漕廊公路2901号科研楼308室 Research Center Room 308, 2901 Caolang Road Jin Shan District Shanghai 201508, CN
Inventors:
徐建青 XU, Jianqing; CN
张晓燕 ZHANG, Xiaoyan; CN
傅卫辉 FU, Weihui; CN
陈健 CHEN, Jian; CN
何涌泉 HE, Yongquan; CN
Agent:
中国专利代理(香港)有限公司 CHINA PATENT AGENT (HK) LTD.; 中国香港特别行政区 香港湾仔港湾道23号鹰君中心22字楼 22/F., Great Eagle Center 23 Harbour Road Wanchai Hong Kong, CN
Priority Data:
201710668628.208.08.2017CN
Title (EN) APPLICATION OF INTERFERON Κ IN THE PREPARATION OF ANTI ENVELOPED VIRUS DRUGS
(FR) APPLICATION DE L’INTERFÉRON K DANS LA PRÉPARATION DE MÉDICAMENTS ANTI-VIRUS ENVELOPPÉS
(ZH) 干扰素κ在制备抗囊膜病毒药物方面的应用
Abstract:
(EN) Disclosed in the present invention is an application of interferon κ (IFN-κ) in the preparation of anti enveloped virus drugs. The nucleotide sequence of the IFN-κ coding gene is shown in SEQ ID NO: 1, the amino acid sequence is shown in SEQ ID NO: 2, and the enveloped viruses include but are not limited to influenza and Zika virus. The present invention found that IFN-κ induces the expression of the antiviral protein IFITM3, and thereby inhibits the infection and replication of influenza virus and Zika virus.
(FR) La présente invention concerne une application de l'interféron κ (IFN-κ) dans la préparation de médicaments anti-virus enveloppés. La séquence de nucléotides du gène codant pour l'IFN-κ est présentée dans SEQ ID No : 1, la séquence d'acides aminés est présentée dans SEQ ID No : 2, et les virus enveloppés comprennent, entre autres, le virus influenza et Zika. La présente invention a découvert que l'IFN-κ induit l'expression de la protéine antivirale IFITM3, et inhibe ainsi l'infection et la réplication du virus influenza et du virus Zika.
(ZH) 本发明公开了干扰素κ(IFN-κ)在制备抗囊膜病毒药物中的应用。所述IFN-κ编码基因的核苷酸序列如SEQ ID NO:1所示,氨基酸序列如SEQ ID NO:2所示,所述囊膜病毒包括但不限于流感和寨卡病毒。本发明发现IFN-κ诱导抗病毒蛋白IFITM3的表达,进而抑制流感病毒和寨卡病毒的感染和复制。
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)