Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2019028646) METHODS AND COMPOSITIONS FOR TREATMENT OF MULTI-DRUG RESISTANT TUMORS
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2019/028646 International Application No.: PCT/CN2017/096331
Publication Date: 14.02.2019 International Filing Date: 08.08.2017
IPC:
A61P 35/00 (2006.01) ,A61K 39/395 (2006.01) ,A61K 48/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48
Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Applicants:
SUN YAT-SEN UNIVERSITY [CN/CN]; 74 Zhongshan 2 Road Guangzhou, Guangdong 510000, CN
Inventors:
HUANG, Yijun; CN
LIU, Danyang; CN
PAN, Juncheng; CN
HU, Yang; CN
ZHU, Zhu; CN
Agent:
WINGUAN PATENT AND TRADEMARK ATTORNEYS; 607, 23 Sicheng Road, Tianhe District Guangzhou, Guangdong 510663, CN
Priority Data:
Title (EN) METHODS AND COMPOSITIONS FOR TREATMENT OF MULTI-DRUG RESISTANT TUMORS
(FR) MÉTHODES ET COMPOSITIONS POUR LE TRAITEMENT DE TUMEURS PRÉSENTANT UNE RÉSISTANCE MULTIPLE AUX MÉDICAMENTS
Abstract:
(EN) Methods for treatment of a multi-drug resistant (MDR) tumor in a subject are disclosed. The methods comprise administering to the subject in need of treatment a therapeutically effective amount of an anti-mycoplasma agent and/or an agent blocking the interaction between membrane protein P37 of mycoplasma and Annexin A2 of host cells of the subject, prior to, at the same time with, or after chemotherapy. Relevant pharmaceutical compositions, kits, uses are also disclosed.
(FR) L'invention concerne des méthodes de traitement d'une tumeur présentant une résistance multiple aux médicaments (MDR) chez un sujet. Les méthodes consistent à administrer au sujet ayant besoin d'un traitement une quantité thérapeutiquement efficace d'un agent anti-mycoplasme et/ou d'un agent bloquant l'interaction entre la protéine membranaire P37 du mycoplasme et l'annexine A2 de cellules hôtes du sujet, avant, pendant ou après une chimiothérapie. L'invention concerne également des compositions pharmaceutiques, des kits et des utilisations appropriés.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)