Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2019028556) METHOD AND SYSTEM FOR ANALYSIS OF DNA METHYLATION AND USE OF SAME TO DETECT CANCER
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2019/028556 International Application No.: PCT/CA2018/050966
Publication Date: 14.02.2019 International Filing Date: 09.08.2018
IPC:
C12Q 1/6844 (2018.01) ,C12Q 1/6806 (2018.01) ,C12Q 1/6813 (2018.01) ,C12Q 1/686 (2018.01) ,C40B 50/06 (2006.01) ,C12Q 1/6886 (2018.01)
[IPC code unknown for C12Q 1/6844][IPC code unknown for C12Q 1/6806][IPC code unknown for C12Q 1/6813][IPC code unknown for C12Q 1/686]
C CHEMISTRY; METALLURGY
40
COMBINATORIAL TECHNOLOGY
B
COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
50
Methods of creating libraries, e.g. combinatorial synthesis
06
Biochemical methods, e.g. using enzymes or whole viable micro-organisms
[IPC code unknown for C12Q 1/6886]
Applicants:
ENRICH BIOSCIENCE INC. [CA/CA]; 33 Struthers Street Etobicoke, Ontario M8V 1Y2, CA
Inventors:
KHARE, Tarang; CA
Agent:
RIDOUT & MAYBEE LLP; 250 University Avenue, 5th Floor Toronto, Ontario M5H 3E5, CA
BOULAKIA, Charles; CA
Priority Data:
62/542,92609.08.2017US
Title (EN) METHOD AND SYSTEM FOR ANALYSIS OF DNA METHYLATION AND USE OF SAME TO DETECT CANCER
(FR) PROCÉDÉ ET SYSTÈME D'ANALYSE DE MÉTHYLATION D'ADN ET UTILISATION DE CEUX-CI POUR DÉTECTER UN CANCER
Abstract:
(EN) Methods for detecting and analyzing low abundance and fragmented nucleic acids are provided, for example for amplifying and analyzing cancer cell DNA having a known pattern of DNA methylation. The example method includes a linear amplification step for targeting an area of interest and creating a complementary strand of the particular area of interest. In an example method a Multiplex Polymerase Chain Reaction (Multiplex PCR) is implemented after the linear amplification step.
(FR) L'invention concerne des procédés de détection et d'analyse d'acides nucléiques fragmentés et peu abondants, par exemple pour amplifier et analyser l'ADN de cellules cancéreuses ayant un motif connu de méthylation d'ADN. Le procédé donné à titre d'exemple comprend une étape d'amplification linéaire pour cibler une zone d'intérêt et créer un brin complémentaire de la zone d'intérêt particulière. Dans un procédé donné à titre d'exemple, une réaction en chaîne par polymérase Multiplex (PCR Multiplex) est mise en œuvre après l'étape d'amplification linéaire.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)