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1. (WO2019028463) LINEAR LIPOPEPTIDE PAENIPEPTINS AND METHODS OF USING THE SAME
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Pub. No.: WO/2019/028463 International Application No.: PCT/US2018/045395
Publication Date: 07.02.2019 International Filing Date: 06.08.2018
IPC:
A61K 35/66 (2015.01) ,A61K 38/14 (2006.01) ,A61P 31/04 (2006.01) ,C07K 7/06 (2006.01) ,C07K 14/47 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
66
Materials from micro-organisms
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
04
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
14
Peptides containing saccharide radicals; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04
Antibacterial agents
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
7
Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04
Linear peptides containing only normal peptide links
06
having 5 to 11 amino acids
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
46
from vertebrates
47
from mammals
Applicants:
BIOVENTURES, LLC [US/US]; 4301 W. Markham Street #831 Little Rock, AZ 72205, US
Inventors:
HUANG, En; US
MOON, Sun, Hee; US
SMELTZER, Mark; US
MEEKER, Daniel; US
Agent:
GULMEN, Tolga, S.; US
WILLIAMS, JR., Edward, R.; US
SOLVESON, George, H.; US
KUBORN, Joseph, D.; US
OLEJNICZAK, Aaron, T.; US
Priority Data:
62/541,20004.08.2017US
Title (EN) LINEAR LIPOPEPTIDE PAENIPEPTINS AND METHODS OF USING THE SAME
(FR) PAENIPEPTINES À LIPOPEPTIDE LINÉAIRE ET PROCÉDÉS D'UTILISATION
Abstract:
(EN) Disclosed herein are linear lipopeptides having antimicrobial and antibiofilm activity. In one aspect of the invention the linear lipopeptide comprising a lipophilic terminus, an amine terminus, and a peptide interposed between the lipophilic terminus and the amine terminus or a salt thereof. The peptide may comprise any of SEQ ID Nos: 1-17 or a derivative thereof. Products comprising the lipopeptides and methods of using the same are also disclosed.
(FR) La présente invention concerne des lipopeptides linéaires ayant une activité antimicrobienne et antibiofilm. Dans un aspect de l'invention, le lipopeptide linéaire comprend une extrémité lipophile, une extrémité amine, et un peptide interposé entre l'extrémité lipophile et l'extrémité amine ou un sel de celui-ci. Le peptide peut comprendre l'une quelconque des SEQ ID NO: 1 à 17 ou d'un dérivé de celles-ci. L’invention concerne en outre les lipopeptides, et des procédés d’utilisation de ceux-ci.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)