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1. (WO2019028295) COMPOSITIONS AND METHODS FOR THE ISOLATION AND/OR GENERATION OF SPECIFIC CD4+ AND CD8+ T-CELL SUBSETS
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Pub. No.: WO/2019/028295 International Application No.: PCT/US2018/045072
Publication Date: 07.02.2019 International Filing Date: 02.08.2018
IPC:
C12N 5/02 (2006.01) ,C12N 5/0783 (2010.01) ,A61K 35/17 (2015.01) ,A61P 35/00 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
02
Propagation of single cells or cells in suspension; Maintenance thereof; Culture media therefor
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07
Animal cells or tissues
071
Vertebrate cells or tissues, e.g. human cells or tissues
078
Cells from blood or from the immune system
0783
T cells; NK cells; Progenitors of T or NK cells
[IPC code unknown for A61K 35/17]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY [US/US]; 9420 Athena Circle La Jolla, California 92037, US
Inventors:
CHEROUTRE, Hilde; US
THIAULT, Nicolas; US
LARANGE, Alexandre; US
IWAYA, Hitoshi; US
Agent:
KONSKI, Antoinette F.; US
IYER, Natasha; US
ARTINGER, Erika L.; US
RAO, Photon; US
SHELTON, Daniel R.; US
Priority Data:
62/540,49802.08.2017US
62/540,50102.08.2017US
Title (EN) COMPOSITIONS AND METHODS FOR THE ISOLATION AND/OR GENERATION OF SPECIFIC CD4+ AND CD8+ T-CELL SUBSETS
(FR) COMPOSITIONS ET PROCÉDÉS POUR L'ISOLEMENT ET/OU LA GÉNÉRATION DE SOUS-ENSEMBLES DE LYMPHOCYTES T CD4+ ET CD8+ SPÉCIFIQUES
Abstract:
(EN) The present disclosure relates to particular subsets of CD4+ and CD8+ T-cells, methods of isolating and generating these cells, compositions comprising these cells, and methods of treatment of a tumor or cancer by administering these cells alone or in combination with each other and/or additional therapies.
(FR) L'invention concerne des sous-ensembles particuliers de lymphocytes T CD4+ et CD8+, des procédés d'isolement et de génération de ces cellules, des compositions comprenant ces cellules et des procédés de traitement d'une tumeur ou d'un cancer par l'administration de ces cellules seules ou en combinaison les unes avec les autres et/ou avec des thérapies supplémentaires.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)