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1. (WO2019028292) ANTI-TREM2 ANTIBODIES AND METHODS OF USE THEREOF
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Pub. No.: WO/2019/028292 International Application No.: PCT/US2018/045068
Publication Date: 07.02.2019 International Filing Date: 02.08.2018
IPC:
C07K 16/28 (2006.01) ,A61K 39/395 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
Applicants:
ALECTOR LLC [US/US]; 151 Oyster Point Boulevard Suite 300 South San Francisco, California 94080, US
Inventors:
SCHWABE, Tina; --
BROWN, Eric; --
KONG, Philip; --
TASSI, Ilaria; --
LEE, Seung-Joo; --
ROSENTHAL, Arnon; --
PEJCHAL, Robert; --
NIELSON, Nels P.; --
Agent:
ZHOU, Jie; US
PESIN-FULOP, Jillian A.; US
Priority Data:
62/541,01903.08.2017US
62/636,09527.02.2018US
Title (EN) ANTI-TREM2 ANTIBODIES AND METHODS OF USE THEREOF
(FR) ANTICORPS ANTI-TREM2 ET LEURS PROCÉDÉS D'UTILISATION
Abstract:
(EN) The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a TREM2 protein, e.g., a mammalian TREM2 or human TREM2, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
(FR) La présente invention concerne d'une manière générale des compositions qui comprennent des anticorps, par ex. , des anticorps monoclonaux, des fragments d'anticorps monoclonaux, etc., qui se lient spécifiquement à une protéine TREM2, par ex. , une TREM2 de mammifère ou une TREM2 humaine, ainsi que l'utilisation de telles compositions dans la prévention, la réduction de risques, ou le traitement d'un individu en ayant besoin.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)