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1. (WO2019028285) USE OF IMMUNE CELL-SPECIFIC GENE EXPRESSION FOR PROGNOSIS OF PROSTATE CANCER AND PREDICTION OF RESPONSIVENESS TO RADIATION THERAPY
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Pub. No.: WO/2019/028285 International Application No.: PCT/US2018/045058
Publication Date: 07.02.2019 International Filing Date: 02.08.2018
IPC:
C12Q 1/6886 (2018.01) ,G16H 50/20 (2018.01)
[IPC code unknown for C12Q 1/6886][IPC code unknown for G16H 50/20]
Applicants:
GENOMEDX, INC. [US/US]; 10355 Science Center Drive, Suite 240 San Diego, California 92121, US
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; 1600 Huron Parkway, 2nd Floor Ann Arbor, Michigan 48109-2590, US
Inventors:
DAVICIONI, Elai; US
ERHO, Nicholas George; CA
LEHRER, Jonathan; CA
FENG, Felix Y.; US
ZHAO, Shuang G.; US
Agent:
MALLON, Joseph J.; US
Priority Data:
62/541,56604.08.2017US
Title (EN) USE OF IMMUNE CELL-SPECIFIC GENE EXPRESSION FOR PROGNOSIS OF PROSTATE CANCER AND PREDICTION OF RESPONSIVENESS TO RADIATION THERAPY
(FR) UTILISATION D'UNE EXPRESSION GÉNIQUE SPÉCIFIQUE DES CELLULES IMMUNITAIRES POUR LE PRONOSTIC DU CANCER DE LA PROSTATE ET LA PRÉDICTION DE LA SENSIBILITÉ À LA RADIOTHÉRAPIE
Abstract:
(EN) Methods, systems, and kits for the diagnosis, prognosis and the determination of cancer progression of prostate cancer in a subject are disclosed. In particular, the disclosure relates to the use of immune cell-specific gene expression in determining prognosis and identifying individuals in need of treatment for prostate cancer who will be responsive to radiation therapy.
(FR) La présente divulgation concerne des méthodes, des systèmes et des kits pour le diagnostic, le pronostic et la détermination de l'évolution d'un cancer de la prostate chez un sujet. En particulier, la présente divulgation concerne l'utilisation de l'expression génique spécifique des cellules immunitaires pour déterminer le pronostic et identifier les individus ayant besoin d'un traitement pour le cancer de la prostate qui seront sensibles à la radiothérapie.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)