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1. (WO2019028283) ANTI-CD33 ANTIBODIES AND METHODS OF USE THEREOF
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Pub. No.: WO/2019/028283 International Application No.: PCT/US2018/045056
Publication Date: 07.02.2019 International Filing Date: 02.08.2018
IPC:
C07K 16/28 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
Applicants:
ALECTOR LLC [US/US]; 151 Oyster Point Boulevard Suite 300 South San Francisco, California 94080, US
Inventors:
CULP, Patricia; --
LAM, Helen; --
ROSENTHAL, Arnon; --
LEE, Seung-Joo; --
NIELSON, Nels P.; --
PEJCHAL, Robert; --
Agent:
ZHOU, Jie; US
TSAO, Patricia; US
Priority Data:
62/541,02403.08.2017US
62/667,38804.05.2018US
Title (EN) ANTI-CD33 ANTIBODIES AND METHODS OF USE THEREOF
(FR) ANTICORPS ANTI-CD33 ET LEURS PROCÉDÉS D'UTILISATION
Abstract:
(EN) The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind one or more epitopes within a CD33 protein, e.g., human CD33 or a mammalian CD33, and have improved and/or enhanced functional characteristics, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
(FR) La présente invention concerne d'une manière générale des compositions qui comprennent des anticorps, par exemple des anticorps monoclonaux, chimériques, humanisés, des fragments d'anticorps, etc., qui se lient spécifiquement à un ou plusieurs épitopes dans une protéine CD33, par exemple CD33 humaine ou CD33 de mammifère, et présentent des caractéristiques fonctionnelles perfectionnées et/ou améliorées, ainsi que l'utilisation desdites compositions dans la prévention, la réduction des risques ou le traitement d'un individu en ayant besoin.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)