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1. (WO2019028235) PESTICIDAL GENES AND METHODS OF USE
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Pub. No.: WO/2019/028235 International Application No.: PCT/US2018/044975
Publication Date: 07.02.2019 International Filing Date: 02.08.2018
IPC:
C07K 14/325 (2006.01) ,C12N 15/82 (2006.01) ,A01N 63/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195
from bacteria
32
from Bacillus (G)
325
Bacillus thuringiensis crystal peptide (delta-endotoxin)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79
Vectors or expression systems specially adapted for eukaryotic hosts
82
for plant cells
A HUMAN NECESSITIES
01
AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
N
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
63
Biocides, pest repellants or attractants, or plant growth regulators containing micro-organisms, viruses, microbial fungi, animals, e.g. nematodes, or substances produced by, or obtained from micro-organisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
Applicants:
AGBIOME, INC. [US/US]; 104 T.W. Alexander Drive Building 1 Durham, North Carolina 27709, US
Inventors:
PARKS, Jessica; US
ROBERTS, Kira Bulazel; US
THAYER, Rebecca E.; US
Agent:
BUCK, B. Logan; US
SHERK, Andrea B.; US
Priority Data:
62/540,75303.08.2017US
62/672,19316.05.2018US
Title (EN) PESTICIDAL GENES AND METHODS OF USE
(FR) GÈNES PESTICIDES ET LEURS PROCÉDÉS D'UTILISATION
Abstract:
(EN) Compositions having pesticidal activity and methods for their use are provided. Compositions include isolated and recombinant polypeptide sequences having pesticidal activity, recombinant and synthetic nucleic acid molecules encoding the pesticidal polypeptides, DNA constructs comprising the nucleic acid molecules, vectors comprising the nucleic acid molecules, host cells comprising the vectors, and antibodies to the pesticidal polypeptides. Nucleotide sequences encoding the polypeptides provided herein can be used in DNA constructs or expression cassettes for transformation and expression in organisms of interest, including microorganisms and plants. The compositions and methods provided herein are useful for production of organisms with enhanced pest resistance or tolerance. Transgenic plants and seeds comprising a nucleotide sequence that encodes a pesticidal protein of the invention are also provided. Such plants are resistant to insects and other pests. Methods are provided for producing the various polypeptides disclosed herein, and for using those polypeptides for controlling or killing a pest.
(FR) La présente invention concerne des compositions présentant une activité pesticide et leurs procédés d'utilisation. Les compositions comprennent des séquences polypeptidiques isolées et de recombinaison présentant une activité pesticide, des molécules d'acides nucléiques de recombinaison et de synthèse codant pour les polypeptides pesticides, des constructions d'ADN comprenant les molécules d'acides nucléiques, des vecteurs comprenant les molécules d'acides nucléiques, des cellules hôtes comprenant les vecteurs et des anticorps dirigés contre les polypeptides pesticides. Des séquences nucléotidiques codant pour les polypeptides peuvent être utilisées dans des constructions ou dans des cassettes d'expression d'ADN en vue d'une transformation et d'une expression dans des organismes d'intérêt, notamment des micro-organismes et des plantes. Les compositions et les procédés selon l'invention sont utiles pour la production d'organismes présentant une résistance ou une tolérance accrue aux parasites. L'invention concerne également des semences et des plantes transgéniques comprenant une séquence nucléotidique qui code pour une protéine pesticide selon l'invention. De telles plantes sont résistantes aux insectes et autres parasites. L'invention concerne en outre des procédés de production des divers polypeptides selon l'invention, et d'utilisation de ces polypeptides pour lutter contre un parasite ou le tuer.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)