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1. (WO2019028106) BIOMARKERS ASSOCIATED WITH PARKINSON'S DISEASE
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2019/028106 International Application No.: PCT/US2018/044750
Publication Date: 07.02.2019 International Filing Date: 01.08.2018
IPC:
A61B 5/00 (2006.01) ,A61K 38/00 (2006.01) ,C07K 7/00 (2006.01) ,C07K 7/08 (2006.01) ,C12Q 1/00 (2006.01) ,G01N 33/48 (2006.01) ,G01N 33/50 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
7
Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
7
Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04
Linear peptides containing only normal peptide links
08
having 12 to 20 amino acids
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
Applicants:
COVE BIO LLC [US/US]; 1539 Meadows Connection Park City, UT 84098, US
Inventors:
LAWYER, Matthew, Carl; US
LAWYER, Carl, Henry; US
Agent:
VANSTONE, Darlene, A.; US
Priority Data:
62/539,62001.08.2017US
62/598,42313.12.2017US
Title (EN) BIOMARKERS ASSOCIATED WITH PARKINSON'S DISEASE
(FR) BIOMARQUEURS ASSOCIÉS À LA MALADIE DE PARKINSON
Abstract:
(EN) Disclosed herein are biomarkers related to the identification or diagnosis of Parkinson's disease in a subject. The disclosed biomarkers and related methods are used to detect or predict Parkinson's disease status in a subject. The disclosed biomarkers and methods can be utilized to determine nature of Parkinson's disease, progression, or responsiveness to a treatment or prophylaxis. Some embodiments include methods of detecting the presence of a biomarker associated with a patient. Some embodiments of the methods include generating a report for clinical disease evaluation or management. Some embodiments of the compositions include associated kits, peptides, binding members, and uses thereof. Also provided are methods and compositions for diagnosing, preventing, and treating Parkinson's disease in a subject in need thereof.
(FR) La présente invention concerne des biomarqueurs liés à l'identification ou au diagnostic de la maladie de Parkinson chez un sujet. Les biomarqueurs et les procédés associés décrits sont utilisés pour détecter ou prédire l'état de la maladie de Parkinson chez un sujet. Les biomarqueurs et les procédés décrits peuvent être utilisés pour déterminer la nature de la maladie de Parkinson, la progression, ou la réactivité à un traitement ou à une prophylaxie. Certains modes de réalisation comprennent des procédés de détection de la présence d'un biomarqueur associé chez le patient. Certains modes de réalisation des procédés comprennent la production d'un rapport pour l'évaluation ou la gestion clinique de la maladie. Certains modes de réalisation des compositions comprennent des kits, des peptides, des éléments de liaison associés, et leurs utilisations. La présente invention concerne également des procédés et des compositions de diagnostic, de prévention, et de traitement de la maladie de Parkinson chez un sujet en ayant besoin.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)