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1. (WO2019028012) METHODS OF USING PEMBROLIZUMAB AND TREBANANIB
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Pub. No.: WO/2019/028012 International Application No.: PCT/US2018/044584
Publication Date: 07.02.2019 International Filing Date: 31.07.2018
IPC:
C07K 16/28 (2006.01) ,C07K 16/22 (2006.01) ,A61K 39/395 (2006.01) ,A61P 35/00 (2006.01) ,G01N 33/574 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
22
against growth factors
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
574
for cancer
Applicants:
DANA-FARBER CANCER INSTITUTE, INC. [US/US]; 450 Brookline Avenue Office of General Counsel 10BP-372A Boston, Massachusetts 02215, US
Inventors:
HODI, Frank Stephen; US
RAHMA, Osama E.; US
Agent:
CLARKE, Daniel W.; US
CHACLAS, George N.; US
COHEN, Jerry; US
COWLES, Christopher R.; US
EMMONS, Richard B.; US
FOLEY, Shawn P.; US
GOLDMAN, Gabriel; US
GOMES, David W.; US
HASAN, Shahid; US
JOBSE, Bruce D.; US
LOPEZ, Orlando; US
MARAIA, Joseph M.; US
MCGRATH, Daniel; US
MILLS, Steven M.; US
MOORE, Ronda P.; US
QUINN, Joseph P.; US
SCHEPPER, Marlo M.; US
SERIO, John C.; US
SORKIN, Paul D.; US
SUSAN, Janine M.; US
Priority Data:
62/539,17631.07.2017US
Title (EN) METHODS OF USING PEMBROLIZUMAB AND TREBANANIB
(FR) PROCÉDÉS D'UTILISATION DE PEMBROLIZUMAB ET DE TRÉBANANIB
Abstract:
(EN) The present invention relates to methods of treating cancer with pembrolizumab and trebananib.
(FR) La présente invention concerne des procédés de traitement du cancer au moyen de pembrolizumab et de trébananib.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)