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1. (WO2019027903) ANTI-CD47 ANTIBODIES AND USES THEREOF
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Pub. No.: WO/2019/027903 International Application No.: PCT/US2018/044384
Publication Date: 07.02.2019 International Filing Date: 30.07.2018
IPC:
C07K 16/28 (2006.01) ,C07K 16/18 (2006.01) ,C07K 16/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
Applicants:
PHANES THERAPEUTICS, INC. [US/US]; 9215 Brown Deer Road Suite B San Diego, CA 92121, US
Inventors:
WANG, Minghan; US
ZOU, Hui; US
OAKS, Joshua; US
JIA, Haiqun; US
Agent:
BARANIAK, Andrew P.; US
AUERBACH, Brian; US
BELISARIO, Martin, G.; US
ELIAS, Ragi, A.; US
BUTLER, Dennis, J.; US
Priority Data:
62/540,11802.08.2017US
62/657,09413.04.2018US
Title (EN) ANTI-CD47 ANTIBODIES AND USES THEREOF
(FR) ANTICORPS ANTI-CD47 ET LEURS UTILISATIONS
Abstract:
(EN) Anti-CD47 antibodies and antigen-binding fragments thereof are described. Also described are nucleic acids encoding the antibodies, compositions comprising the antibodies, and methods of producing the antibodies and using the antibodies for treating or preventing diseases such as cancer, inflammatory disease, infectious disease, atherosclerosis, cardiovascular disease, metabolic disease, radiation-induced injury, and/or autoimmune disease.
(FR) L'invention concerne des anticorps anti-CD47 et des fragments de liaison à l'antigène associé. L'invention concerne également des acides nucléiques codant pour les anticorps, des compositions comprenant les anticorps, et des procédés de production des anticorps et d'utilisation des anticorps pour traiter ou prévenir des maladies telles que le cancer, des maladies inflammatoires, des maladies infectieuses, l’athérosclérose, des maladies cardiovasculaires, des maladies métaboliques, des blessures induites par un rayonnement et/ou des maladies auto-immunes.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)