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1. (WO2019027884) METHODS FOR DETECTING DISORDERS RELATED TO CALCIUM DISCHARGE FROM INTRACELLULAR STORES
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Pub. No.: WO/2019/027884 International Application No.: PCT/US2018/044346
Publication Date: 07.02.2019 International Filing Date: 30.07.2018
IPC:
G06F 19/00 (2018.01)
G PHYSICS
06
COMPUTING; CALCULATING; COUNTING
F
ELECTRIC DIGITAL DATA PROCESSING
19
Digital computing or data processing equipment or methods, specially adapted for specific applications
Applicants:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 1111 Franklin Street, Twelfth Floor Oakland, California 94607, US
Inventors:
FOMINA, Alla F.; US
Agent:
ROBERTS, Byron N.; US
HAO, Joe C.; US
PRESLEY, Andrew D.; US
Priority Data:
62/539,35431.07.2017US
Title (EN) METHODS FOR DETECTING DISORDERS RELATED TO CALCIUM DISCHARGE FROM INTRACELLULAR STORES
(FR) PROCÉDÉS DE DÉTECTION DE TROUBLES LIÉS À UNE DÉCHARGE DE CALCIUM PROVENANT DE STOCKAGES INTRACELLULAIRES
Abstract:
(EN) Provided herein are methods for determining whether a subject has an increased likelihood of having a disorder related to abnormal intracellular calcium store discharge. In some embodiments, the method is useful for determining whether the subject has an increased likelihood of having a neurodegenerative disease, skeletal muscle disease, cardiac muscle disease, autoimmune disease, cancer, diabetes, or has been exposed to an environmental pollutant. Kits are also provided herein.
(FR) L'invention concerne des procédés permettant de déterminer si un sujet présente une probabilité accrue d'avoir un trouble lié à une décharge anormale de stockage de calcium intracellulaire. Dans certains modes de réalisation, le procédé permet de déterminer si le sujet présente une probabilité accrue de souffrir d'une maladie neurodégénérative, d'une maladie du muscle squelettique, d'une maladie du muscle cardiaque, d'une maladie auto-immune, du cancer, du diabète, ou s'il a été exposé à un polluant environnemental. L'invention concerne également des kits.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)