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1. (WO2019026827) THERMOLYSIN SOLUTION
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Pub. No.: WO/2019/026827 International Application No.: PCT/JP2018/028409
Publication Date: 07.02.2019 International Filing Date: 30.07.2018
IPC:
C12N 9/54 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9
Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
14
Hydrolases (3.)
48
acting on peptide bonds, e.g. thromboplastin, leucine aminopeptidase (3.4)
50
Proteinases
52
derived from bacteria
54
bacteria being Bacillus
Applicants:
天野エンザイム株式会社 AMANO ENZYME INC. [JP/JP]; 愛知県名古屋市中区錦1丁目2番7号 2-7, Nishiki 1-chome, Naka-ku, Nagoya-shi, Aichi 4608630, JP
Inventors:
古川 和寛 FURUKAWA, Kazuhiro; JP
Agent:
田中 順也 TANAKA, Junya; JP
水谷 馨也 MIZUTANI, Keiya; JP
迫田 恭子 SAKODA, Kyoko; JP
Priority Data:
2017-14822131.07.2017JP
Title (EN) THERMOLYSIN SOLUTION
(FR) SOLUTION DE THERMOLYSINE
(JA) サーモリシン液剤
Abstract:
(EN) Provided is a thermolysin solution having further improved stability. The stability can be further improved by configuring a thermolysin solution that contains thermolysin in a concentration of 0.1 mg/mL or higher and has the pH adjusted to higher than 9.0, preferably a pH of 9.5-11.5.
(FR) L'invention concerne une solution de thermolysine présentant une stabilité améliorée. La stabilité peut être encore améliorée par la configuration d'une solution de thermolysine contenant de la thermolysine à une concentration supérieure ou égale à 0,1 mg/mL et présentant un pH ajusté supérieur à 9,0, de préférence un pH de 9,5-11,5.
(JA) 安定性をより向上させたサーモリシン液剤を提供する。サーモリシンを、0.1mg/mL以上となる濃度で含み、且つpHが9.0超、好ましくは、pHが9.5~11.5に調整されているサーモリシン液剤とすることで、安定性をより向上させることができる。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)