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1. (WO2019026230) METHOD FOR PRODUCING CERAMIDE
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Pub. No.: WO/2019/026230 International Application No.: PCT/JP2017/028219
Publication Date: 07.02.2019 International Filing Date: 03.08.2017
Chapter 2 Demand Filed: 06.04.2018
IPC:
C11B 11/00 (2006.01) ,A61K 8/68 (2006.01) ,A61K 35/60 (2006.01) ,A61P 17/16 (2006.01) ,A61Q 19/00 (2006.01)
C CHEMISTRY; METALLURGY
11
ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
B
PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
11
Recovery or refining of other fatty substances, e.g. lanolin, waxes
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
18
characterised by the composition
30
containing organic compounds
68
Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
56
Materials from animals other than mammals or birds
60
Fish
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17
Drugs for dermatological disorders
16
Emollients or protectives, e.g. against radiation
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
Q
SPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19
Preparations for care of the skin
Applicants:
株式会社双葉紙器 KABUSHIKI KAISHA FUTABA SHIKI [JP/JP]; 福島県双葉郡浪江町大字幾世橋字知命寺20番地 20, Aza Chimeiji, Oaza Kiyohashi, Namie-machi, Futaba-gun, Fukushima 9791513, JP
Inventors:
熊川 喜仁 KUMAKAWA, Yoshihito; JP
大隈 信行 OKUMA, Nobuyuki; JP
Agent:
特許業務法人創成国際特許事務所 SATO & ASSOCIATES; 東京都新宿区西新宿6-24-1 西新宿三井ビルディング 18階 Nishi-Shinjuku Mitsui Building 18F, 24-1, Nishi-Shinjuku 6-chome, Shinjuku-ku, Tokyo 1600023, JP
Priority Data:
Title (EN) METHOD FOR PRODUCING CERAMIDE
(FR) PROCÉDÉ DE PRODUCTION DE CÉRAMIDE
(JA) セラミドの製造方法
Abstract:
(EN) Provided is a method which is for producing ceramide and is capable of selectively separating ceramide from an extract extracted from fish meat by using an organic solvent. Fish meat 1 is stirred in a first mixed solvent 2, a ceramide and a ceramide ciliatine are extracted from the mixed solvent 2, filtrate 5 obtained by filtering the mixed solvent 2 is dry-hardened by distillation under reduced pressure to thereby obtain a mixture 6, a second mixed solvent 11 is added to the mixture 6, the resultant mixture is stirred, and then left standing to be separated into a hexane phase 13 and an ethanol-aqueous phase 14, and a ceramide 15 is obtained from the hexane phase 13.
(FR) L'invention concerne un procédé qui permet de produire un céramide et qui est capable de séparer sélectivement un céramide d'un extrait qui est extrait de la chair de poisson en utilisant un solvant organique. De la chair de poisson (1) est agitée dans un premier solvant mélangé (2). Un céramide et une ciliatine de céramide sont extraites du solvant mélangé (2). Le filtrat (5) obtenu par filtration du solvant mélangé (2) est durci à sec par distillation sous pression réduite pour obtenir ainsi un mélange (6). Un deuxième solvant mélangé (11) est ajouté au mélange (6), le mélange résultant est agité, puis laissé au repos pour être séparé en une phase hexane (13) et une phase éthanol-aqueuse (14), et un céramide (15) est obtenu à partir de la phase hexane (13).
(JA) 魚肉から有機溶媒により抽出される抽出物から、セラミドを選択的に分離することができるセラミドの製造方法を提供する。魚肉1を第1の混合溶媒2中で撹拌し、セラミドとセラミドシリアチンとを混合溶媒2中に抽出し、混合溶媒2を濾過して得られた濾液5を減圧蒸留により乾固して混合物6を得て、混合物6に第2の混合溶媒11を加え、撹拌した後、静置することにより、ヘキサン相13とエタノール-水相14とに分離し、ヘキサン相13からセラミド15を得る。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)