Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2019025961) mTOR ENHACERS AND USES THEREOF TO IMPROVE SPERM QUALITY AND FUNCTION DURING STORAGE
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2019/025961 International Application No.: PCT/IB2018/055715
Publication Date: 07.02.2019 International Filing Date: 31.07.2018
IPC:
A61K 35/52 (2015.01) ,A01N 1/02 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
12
Materials from mammals or birds
48
Reproductive organs; Embryos
52
Sperm
A HUMAN NECESSITIES
01
AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
N
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
1
Preservation of bodies of humans or animals, or parts thereof
02
Preservation of living parts
Applicants:
UNIVERSIDADE DO PORTO [PT/PT]; Praça Gomes Teixeira, S/N, 4º, S.419 4099-002 Porto, PT
Inventors:
GOUVEIA ALVES, Marco Aurélio; PT
FONTES OLIVEIRA, Carlos Pedro; PT
DA SILVA LEITE DE SOUSA, Mário Manuel; PT
BOLÉO TELES DE JESUS, Tito Miguel; PT
PINTO DE ALMEIDA, Susana Paula; PT
Agent:
PEREIRA DA CRUZ, João; PT
Priority Data:
11023102.08.2017PT
Title (EN) mTOR ENHACERS AND USES THEREOF TO IMPROVE SPERM QUALITY AND FUNCTION DURING STORAGE
(FR) ACTIVATEURS DE MTOR ET LEURS UTILISATIONS POUR AMÉLIORER LA QUALITÉ ET LA FONCTION DU SPERME PENDANT LE STOCKAGE
Abstract:
(EN) The present invention refers to field of assisted reproductive technologies, in particular to a sperm storage media, and describes mTOR enhancers, preferably the mTOR activator MHY 1485, as supplement for storage media, said supplemented media increasing sperm motility and viability during short-term room temperature storage, while sustaining the metabolic rates, without changing its fertilization potential (capacitation) and DNA integrity.
(FR) La présente invention concerne le domaine des technologies d'aide à la procréation et, en particulier, un milieu de stockage du sperme, ainsi que des activateurs de mTOR, de préférence l'activateur de mTOR MHY 1485, en tant qu'adjuvant pour milieu de stockage, lesdits milieux enrichis augmentant la motilité et la viabilité du sperme pendant le stockage à température ambiante de courte durée, tout en préservant les taux de métabolisme, et ce, sans modifier son potentiel de fécondation (capacitation) et l'intégrité de l'ADN.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)