Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2019025865) METHODS AND COMPOSITIONS FOR LIGAND DIRECTED ANTIBODY DESIGN
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2019/025865 International Application No.: PCT/IB2018/001000
Publication Date: 07.02.2019 International Filing Date: 03.08.2018
IPC:
C07K 16/00 (2006.01) ,C07K 16/28 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
Applicants:
ABCAM PLC [GB/GB]; 330 Cambridge Science Park Cambridge CB4 OFL, GB
Inventors:
WEINER, Michael; GB
KISS, Margaret; GB
ZHAO, Qi; GB
Priority Data:
62/541,53304.08.2017US
Title (EN) METHODS AND COMPOSITIONS FOR LIGAND DIRECTED ANTIBODY DESIGN
(FR) PROCÉDÉS ET COMPOSITIONS DE CONCEPTION D'ANTICORPS DIRIGÉE PAR LIGAND
Abstract:
(EN) The present disclosure provides, among other things, methods for generating antibodies against a target protein. In some embodiments, a library is provided comprising a plurality of tether antibodies comprising an antigen binding region and a ligand that binds to a target protein. In some embodiments, a library is provided comprising a plurality of candidate antibodies for binding to a target protein.
(FR) La présente invention concerne, entre autres, des procédés de génération d'anticorps contre une protéine cible. Dans certains modes de réalisation, la présente invention concerne une bibliothèque comprenant une pluralité d'anticorps d'attache comprenant une région de liaison à l'antigène et un ligand qui se lie à une protéine cible. Dans certains modes de réalisation, la présente invention concerne une bibliothèque comprenant une pluralité d'anticorps candidats pour se lier à une protéine cible.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)