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1. (WO2019025580) MICROORGANISM AND METHOD FOR IMPROVED 1,3-PROPANEDIOL PRODUCTION BY FERMENTATION ON A CULTURE MEDIUM WITH HIGH GLYCERINE CONTENT
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Pub. No.: WO/2019/025580 International Application No.: PCT/EP2018/071104
Publication Date: 07.02.2019 International Filing Date: 03.08.2018
IPC:
C12P 7/18 (2006.01) ,C12R 1/145 (2006.01) ,C12N 1/36 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
7
Preparation of oxygen-containing organic compounds
02
containing a hydroxy group
04
acyclic
18
polyhydric
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
R
INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C-C12Q75
1
Micro-organisms
01
Bacteria or actinomycetales
145
Clostridium
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1
Micro-organisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving micro-organisms or compositions thereof; Processes of preparing or isolating a composition containing a micro-organism; Culture media therefor
36
Adaptation or attenuation of cells
Applicants:
METABOLIC EXPLORER [FR/FR]; BIOPOLE CLERMONT-LIMAGNE 63360 SAINT BEAUZIRE, FR
Inventors:
RAYNAUD, Céline; FR
TOURRASSE, Olivier; FR
DUMOULIN, Nadège; FR
Agent:
REGIMBEAU; 20, rue de Chazelles 75847 PARIS CEDEX 17, FR
Priority Data:
17306044.304.08.2017EP
Title (EN) MICROORGANISM AND METHOD FOR IMPROVED 1,3-PROPANEDIOL PRODUCTION BY FERMENTATION ON A CULTURE MEDIUM WITH HIGH GLYCERINE CONTENT
(FR) MICRO-ORGANISME ET PROCÉDÉ DE PRODUCTION AMÉLIORÉE DE 1,3-PROPANEDIOL PAR FERMENTATION SUR UN MILIEU DE CULTURE À TENEUR ÉLEVÉE EN GLYCÉRINE
Abstract:
(EN) The present invention concerns a new method for the production of 1,3- propanediol comprising culturing a recombinant microorganism converting glycerol into 1,3-propanediol and overexpressing the hcpR and/or frdX gene on a medium comprising glycerine. A recombinant microorganism for the production of 1,3 propanediol from glycerol, wherein said microorganism converts glycerol into 1,3-propanediol and 10 overexpresses the hcpR and/or the frdX gene.
(FR) La présente invention concerne un nouveau procédé destiné à la production de 1,3-propanediol, comprenant la culture d'un micro-organisme recombinant convertissant le glycérol en 1,3-propanediol et surexprimant le gène hcpR et/ou frdX sur un milieu comprenant de la glycérine. La présente invention concerne également un micro-organisme recombinant destiné à la production de 1,3-propanediol à partir de glycérol, ledit micro-organisme convertissant le glycérol en 1,3-propanediol et surexprimant le gène hcpR et/ou frdX.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)