Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2019025548) A SYNERGISTIC COMPOSITION AS A PROMOTER OF AUTOPHAGY
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2019/025548 International Application No.: PCT/EP2018/071005
Publication Date: 07.02.2019 International Filing Date: 02.08.2018
IPC:
A61K 36/53 (2006.01) ,A61K 31/4188 (2006.01) ,A61K 31/132 (2006.01) ,A61P 17/14 (2006.01) ,A61K 8/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36
Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18
Magnoliophyta (angiosperms)
185
Magnoliopsida (dicotyledons)
53
Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
4164
1,3-Diazoles
4188
condensed with heterocyclic ring systems, e.g. biotin, sorbinil
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
13
Amines, e.g. amantadine
132
having two or more amino groups, e.g. spermidine, putrescine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17
Drugs for dermatological disorders
14
for baldness or alopecia
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
Applicants:
GIULIANI S.P.A. [IT/IT]; Via Palagi 2 20129 Milano, IT
Inventors:
GIULIANI, Giammaria; CH
PAUS, Ralf; DE
GRIMALDI, Benedetto; IT
MARZANI, Barbara; IT
BARONI, Sergio; IT
Agent:
COPPO, Alessandro; IT
GERVASI, Gemma; IT
PALLINI GERVASI, Diego; IT
CATTANEO, Elisabetta; IT
PALLADINO, Massimo; IT
VALENZA, Silvia; IT
ZACCARO, Elisabetta; IT
BRIGHENTI, Livio; IT
CELONA, Antonio; IT
DE BORTOLI, Tiziano; IT
SAVI, Massimiliano; IT
TORTI, Carlo Maria Emilio; IT
CINQUANTINI, Bruno; IT
CONTADIN, Giorgio; IT
Priority Data:
10201700008968003.08.2017IT
Title (EN) A SYNERGISTIC COMPOSITION AS A PROMOTER OF AUTOPHAGY
(FR) COMPOSITION SYNERGIQUE EN TANT QUE PROMOTEUR DE L'AUTOPHAGIE
Abstract:
(EN) The invention relates to a synergistic composition comprising a dry extract of plant of genus Galeopsis and a compound promoting autophagy selected from biotin and R-N1-spermidine or a salt thereof, wherein R is hydrogen or methyl and mixtures thereof. The synergistic compositions according to the invention may be in the form of a topical formulation or oral formulation and is useful as a promoter of autophagy especially in cells of human scalp hair follicles and in promoting hair growth and/or in the treatment of hair thinning or hair loss.
(FR) L'invention concerne une composition synergique comprenant un extrait sec d'une plante du genre Galeopsis ainsi qu'un composé favorisant l'autophagie sélectionné entre la biotine et la R-N-spermidine ou un sel de cette dernière, R étant un hydrogène ou un méthyle, et des mélanges de ces dermières. Les compositions synergiques selon l'invention peuvent se présenter sous la forme d'une formulation topique ou d'une formulation pour la voie orale et sont utilisables comme promoteur de l'autophagie, en particulier au niveau des cellules des follicules pileux du cuir chevelu chez l'humain, et pour favoriser la pousse des cheveux et/ou dans le traitement des cheveux clairsemés ou de la perte des cheveux.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)