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1. (WO2019025433) ANTICANCER PEPTIDES
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Pub. No.: WO/2019/025433 International Application No.: PCT/EP2018/070716
Publication Date: 07.02.2019 International Filing Date: 31.07.2018
IPC:
C07K 14/82 (2006.01) ,A61K 38/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
82
Translation products from oncogenes
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
Applicants:
IDP DISCOVERY PHARMA, S.L. [ES/ES]; Baldiri Reixac Nº 4 08028 BARCELONA, ES
Inventors:
NEVOLA, Laura; ES
ESTEBAN MARTÍN, Santiago; ES
Agent:
ZBM PATENTS - ZEA, BARLOCCI & MARKVARDSEN; Pl. Catalunya, 1 2nd floor 08002 BARCELONA, ES
Priority Data:
17382533.202.08.2017EP
Title (EN) ANTICANCER PEPTIDES
(FR) PEPTIDES À ACTIVITÉ ANTICANCÉREUSE
Abstract:
(EN) The present invention provides a peptide of formula (I) or a pharmaceutical salt thereof, as well as fusion peptides and pharmaceutical compositions comprising it; or, alternatively, the peptide or pharmaceutical salt thereof is one which has an amino acid sequence with an identity from 85% to 95% with respect to sequence SEQ ID NO: 25, 26, 27 or 28. The peptides of the invention show anticancer activity. Formula (I).
(FR) La présente invention concerne un peptide de formule (I) ou un sel pharmaceutique de celui-ci, ainsi que des peptides de fusion et des compositions pharmaceutiques le comprenant ; ou, en variante, le peptide ou son sel pharmaceutique est un peptide qui a une séquence d'acides aminés ayant une identité de 85 % à 95 % par rapport à la séquence SEQ ID NO : 25, 26, 27 ou 28. Les peptides de l'invention présentent une activité anticancéreuse. Formule (I).
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)