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1. (WO2019025424) COMPOUNDS FOR TREATING SYNUCLEINOPATHIES
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2019/025424 International Application No.: PCT/EP2018/070694
Publication Date: 07.02.2019 International Filing Date: 31.07.2018
IPC:
C07D 405/06 (2006.01) ,A61P 25/00 (2006.01) ,A61K 31/4525 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
405
Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
02
containing two hetero rings
06
linked by a carbon chain containing only aliphatic carbon atoms
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
445
Non-condensed piperidines, e.g. piperocaine
4523
containing further heterocyclic ring systems
4525
containing a five-membered ring with oxygen as a ring hetero atom
Applicants:
UNIVERSITAT AUTONOMA DE BARCELONA [ES/ES]; Oficina de Valorització i Patents Edifici A- Rectorat Campus universitari s/n 08193 Bellaterra (Cerdanyola del Valles), ES
UNIVERSIDAD DE ZARAGOZA [ES/ES]; OTRI c/ Pedro Cerbuna, 12 50009 ZARAGOZA, ES
Inventors:
VENTURA ZAMORA, Salvador; ES
PEÑA DÍAZ, Samuel; ES
DALFO CAPELLA, Esther; ES
PUJOLS PUJOL, Jordi; ES
SANCHO SANZ, Javier; ES
CONDE GIMÉNEZ, María; ES
Priority Data:
17382554.804.08.2017EP
Title (EN) COMPOUNDS FOR TREATING SYNUCLEINOPATHIES
(FR) COMPOSÉS PERMETTANT DE TRAITER DES SYNUCLÉINOPATHIES
Abstract:
(EN) The present invention relates to compounds able to inhibit α-synuclein aggregation,their use in the treatment or prophylaxis of a synucleinopathy and to pharmaceutical compositions comprising said compounds.
(FR) La présente invention concerne des composés capables d'inhiber l'agrégation d'alpha-synucléine, leur utilisation dans le traitement ou la prophylaxie d'une synucléinopathie et des compositions pharmaceutiques comprenant lesdits composés.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)