Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2019024949) MANUFACTURING METHOD OF ORAL DOSAGE FORM CONTAINING BERBERINE, ORAL DOSAGE FORM CONTAINING BERBERINE AND USE THEREOF
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2019/024949 International Application No.: PCT/CZ2017/050033
Publication Date: 07.02.2019 International Filing Date: 02.08.2017
IPC:
A61K 31/4375 (2006.01) ,A61K 9/20 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
4353
ortho- or peri-condensed with heterocyclic ring systems
4375
the heterocyclic ring system containing a six-membered ring having nitrogen as a ring hetero atom, e.g. quinolizines, naphthyridines, berberine, vincamine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
Applicants:
PRO.MED.CS PRAHA A.S. [CZ/CZ]; Telcska 377/1 140 00 Praha 4, CZ
Inventors:
BOUSKOVA, Aneta; CZ
LISAL, Jiri; CZ
REZAC, Jaroslav; CZ
SVOBODA, Zbynek; CZ
Agent:
HARTVICHOVA, Katerina; CZ
Priority Data:
Title (EN) MANUFACTURING METHOD OF ORAL DOSAGE FORM CONTAINING BERBERINE, ORAL DOSAGE FORM CONTAINING BERBERINE AND USE THEREOF
(FR) PROCÉDÉ DE FABRICATION DE FORME POSOLOGIQUE ORALE CONTENANT DE LA BERBÉRINE, FORME POSOLOGIQUE ORALE CONTENANT DE LA BERBÉRINE ET SON UTILISATION
Abstract:
(EN) Title: Manufacturing method of oral dosage form containing berberine, oral dosage form containing berberine and use thereof 5 The present invention relates to a manufacturing method of oral dosage form containing berberine, which contains steps of homogenization of berberine with at least one glidant to obtain a homogenous mixture, homogenization of the mixture with at least one filler; homogenization of the resulting mixture with at least one lubricant, followed by dry granulation and sieving, and further 10 homogenization of the granulated mixture with at least one disintegrant, followed by homogenization of the mixture with at least one lubricant, and preparation of oral dosage form selected from tablets, pills, orally disintegrating tablets, using the final homogenized mixture. The invention further relates to the oral dosage form containing berberine and to the use thereof.
(FR) La présente invention concerne un procédé de fabrication de forme posologique orale contenant de la berbérine, qui contient les étapes suivantes : l'homogénéisation de la berbérine avec au moins un agents facilitant l'écoulement pour obtenir un mélange homogène, l'homogénéisation du mélange avec au moins une charge; l'homogénéisation du mélange résultant avec au moins un lubrifiant, suivi d'une granulation et d'un tamisage à sec, puis l'homogénéisation du mélange granulé avec au moins un délitant, suivie d'une homogénéisation du mélange avec au moins un lubrifiant, et la préparation d'une forme posologique orale choisie parmi les comprimés, les pilules, les comprimés à désintégration orale, à l'aide du mélange homogénéisé final. L'invention concerne en outre la forme posologique orale contenant de la berbérine et son utilisation.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)