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1. (WO2019024814) MEDICATION FOR INHIBITING DNA-PKCS
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Pub. No.: WO/2019/024814 International Application No.: PCT/CN2018/097609
Publication Date: 07.02.2019 International Filing Date: 27.07.2018
IPC:
A61K 38/17 (2006.01) ,A61P 35/00 (2006.01) ,A61K 31/704 (2006.01) ,A61K 31/7048 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7028
Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
7034
attached to a carbocyclic compound, e.g. phloridzin
704
attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin, digitoxin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7042
Compounds having saccharide radicals and heterocyclic rings
7048
having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
Applicants:
清华大学 TSINGHUA UNIVERSITY [CN/CN]; 中国北京市 海淀区清华园1号 No.1, Qinghuayuan, Haidian District Beijing 100084, CN
北京普罗吉生物科技发展有限公司 BEIJING PROTGEN LTD. [CN/CN]; 中国北京市 海淀区开拓路5号B412 Room B412, No.5 Kaituo Road, Haidian District Beijing 100085, CN
Inventors:
罗永章 LUO, Yongzhang; CN
贾琳 JIA, Lin; CN
常国栋 CHANG, Guodong; CN
Agent:
北京华睿卓成知识产权代理事务所(普通合伙) CHENG & PENG INTELLECTUAL PROPERTY LAW OFFICE; 中国北京市 东城区广渠门内大街90号楼新裕商务大厦B座704 704, Block B, Xinyu Commercial Building 90 Guangqumen Inner Street, Dongcheng District Beijing 100062, CN
Priority Data:
201710638033.230.07.2017CN
201710733900.024.08.2017CN
Title (EN) MEDICATION FOR INHIBITING DNA-PKCS
(FR) MÉDICAMENT POUR INHIBER L'ADN-PKCS
(ZH) 抑制DNA依赖蛋白激酶催化亚基的药物
Abstract:
(EN) A method for treating a tumor or cancer by means of a treatment scheme of using endostatin in combination with induction of DNA double-strand breaks, and a medication. The method and composition are used for treating a tumor or cancer related to loss of p53 function, or a tumor or cancer occurring when p53 function is normal.
(FR) L'invention concerne une méthode de traitement d'une tumeur ou d'un cancer au moyen d'un schéma de traitement consistant à utiliser de l'endostatine en combinaison avec l'induction de cassures double brin d'ADN, et un médicament. La méthode et la composition sont utilisées pour traiter une tumeur ou un cancer lié à la perte de la fonction de p53, ou une tumeur ou un cancer se produisant lorsque la fonction de p53 est normale.
(ZH) 使用血管内皮抑制素联合诱导DNA双链断裂的治疗方案治疗肿瘤或癌症的方法和药物。所述的方法和组合物用于治疗P53功能缺失的肿瘤或癌症,或者P53功能正常的肿瘤或癌症。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)