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1. (WO2019024433) OPHTHALMIC COMPOSITION OF AMINO AMANTADINE MONONITRATE COMPOUND AND PREPARATION AND APPLICATION THEREOF
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Pub. No.: WO/2019/024433 International Application No.: PCT/CN2018/000282
Publication Date: 07.02.2019 International Filing Date: 01.08.2018
IPC:
A61K 31/12 (2006.01) ,A61K 9/06 (2006.01) ,A61K 9/08 (2006.01) ,A61K 47/36 (2006.01) ,A61K 47/38 (2006.01) ,A61K 47/10 (2006.01) ,A61K 47/32 (2006.01) ,A61P 27/02 (2006.01) ,A61P 27/06 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
12
Ketones
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
06
Ointments; Bases therefor
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
08
Solutions
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
36
Polysaccharides; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
36
Polysaccharides; Derivatives thereof
38
Cellulose; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
08
containing oxygen
10
Alcohols; Phenols; Salts thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
32
Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
27
Drugs for disorders of the senses
02
Ophthalmic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
27
Drugs for disorders of the senses
02
Ophthalmic agents
06
Antiglaucoma agents or miotics
Applicants:
佛山喜鹊医药有限公司 FOSHAN MAGPIE PHARMACEUTICALS CO., LTD. [CN/CN]; 中国广东省佛山市 顺德区乐从镇岭南大道2号中欧中心A栋5层531室 Room 531, Floor 5, Building A, Sino-European Center, No.2 Lingnan Road, Lecong Town, Shunde District Foshan, Guangdong 528300, CN
Inventors:
王玉强 WANG, Yuqiang; CN
孙业伟 SUN, Yewei; CN
张在军 ZHANG, Zaijun; CN
张高小 ZHANG, Gaoxiao; CN
于沛 YU, Pei; CN
易鹏 YI, Peng; CN
Agent:
北京攀腾专利代理事务所 PANTERRAIN IP ATTORNEYS; CN
Priority Data:
201710660958.704.08.2017CN
Title (EN) OPHTHALMIC COMPOSITION OF AMINO AMANTADINE MONONITRATE COMPOUND AND PREPARATION AND APPLICATION THEREOF
(FR) COMPOSITION OPHTALMIQUE À BASE D'UN COMPOSÉ DE MONONITRATE D'AMINOAMANTADINE, SA PRÉPARATION ET SON APPLICATION
(ZH) 氨基金刚烷胺单硝酸酯类化合物眼用组合物及其制剂和应用
Abstract:
(EN) Provided are an ophthalmic composition comprising an amino amantadine mononitrate compound in a mass/volume ratio of 0.001-5% and an application of the ophthalmic composition in preparing a drug for preventing or treating glaucoma, high intraocular pressure, or an eye disease with retinal ganglion cell damage.
(FR) L'invention concerne une composition ophtalmique comprenant un composé de mononitrate d'aminoamantadine dans un rapport poids/volume de 0,001 à 5 % et une application de ladite composition ophtalmique dans la préparation d'un médicament destiné à prévenir ou à traiter le glaucome, une pression intraoculaire élevée, ou une maladie oculaire impliquant une lésion des cellules ganglionnaires de la rétine.
(ZH) 包含质量体积比为0.001%~5%的氨基金刚烷胺单硝酸酯类化合物的眼用组合物,以及该眼用组合物在制备预防和治疗青光眼、眼内压升高或伴有视网膜神经节细胞损伤的眼科疾病药物中的应用。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)