Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2019024220) ENGINEERED BACTERIA AND APPLICATION THEREOF
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2019/024220 International Application No.: PCT/CN2017/104178
Publication Date: 07.02.2019 International Filing Date: 29.09.2017
IPC:
C12N 1/21 (2006.01) ,C12P 7/42 (2006.01) ,C12R 1/19 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1
Micro-organisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving micro-organisms or compositions thereof; Processes of preparing or isolating a composition containing a micro-organism; Culture media therefor
20
Bacteria; Culture media therefor
21
modified by introduction of foreign genetic material
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
7
Preparation of oxygen-containing organic compounds
40
containing a carboxyl group
42
Hydroxy carboxylic acids
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
R
INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C-C12Q75
1
Micro-organisms
01
Bacteria or actinomycetales
185
Escherichia
19
Escherichia coli
Applicants:
江南大学 JIANGNAN UNIVERSITY [CN/CN]; 中国江苏省无锡市 通沙路898号南楼7层耿晓岳 Xiaoyue Geng F7 south building, No.898 tongsha road wuxi, Jiangsu 214122, CN
西北大学 NORTHWEST UNIVERSITY [CN/CN]; 中国陕西省西安市 太白北路229号耿晓岳 Xiaoyue Geng No.229,Taibai North-Road Xian, Shaanxi 710000, CN
Inventors:
蔡宇杰 CAI, Yujie; CN
熊天真 XIONG, Tianzhen; CN
刘金彬 LIU, Jinbin; CN
丁彦蕊 DING, Yanrui; CN
白亚军 BAI, Yajun; CN
郑晓晖 ZHENG, Xiaohui; CN
Agent:
哈尔滨市阳光惠远知识产权代理有限公司 HARBIN SHINEIP INTELLECTUAL PROPERTY AGENCY CO.,LTD.; 中国黑龙江省哈尔滨市 松北区科技一街99号18栋E501耿晓岳 Xiaoyue Geng Room E501, Building 18,Science and technology 1st street No.99,District Songbei Harbin, Heilongjiang 150028, CN
Priority Data:
201710652387202.08.2017CN
Title (EN) ENGINEERED BACTERIA AND APPLICATION THEREOF
(FR) BACTÉRIE MODIFIÉE ET APPLICATION ASSOCIÉE
(ZH) 一种工程菌及其应用
Abstract:
(EN) Provided is a genetically engineered E. coli bacteria, which is characterized in that: an L-amino acid oxidase gene, an α-hydroxycarboxylic acid dehydrogenase gene, and a gene that is capable of reducing NAD(P) are introduced into the E. coli bacteria. Further provided is a method for producing the α-hydroxycarboxylic acid by using the recombinant E. coli bacteria.
(FR) L'invention concerne une bactérie E. coli génétiquement modifiée, qui est caractérisée en ce que : un gène de la L-aminoacide oxydase, un gène de l'acide α-hydroxycarboxylique déshydrogénase et un gène qui est capable de réduire le NAD(P) sont introduits dans la bactérie E. coli. L'invention concerne en outre un procédé de production de l'acide α-hydroxycarboxylique à l'aide de la bactérie E. coli recombinée.
(ZH) 提供了一种大肠杆菌基因工程菌,其特征在于:所述大肠杆菌导入了L-氨基酸氧化酶基因、α-羟基羧酸脱氢酶基因和可以还原NAD(P)的基因。还提供了利用上述重组大肠杆菌生产α-羟基羧酸的方法。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)