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1. (WO2019023960) FUNCTIONALIZED MESH AND FLUIDIC APPARATUS FOR CAPTURING CELLS OR MOLECULES IN SOLUTION
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Pub. No.: WO/2019/023960 International Application No.: PCT/CN2017/095556
Publication Date: 07.02.2019 International Filing Date: 02.08.2017
IPC:
C12M 1/12 (2006.01) ,C12M 1/34 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
M
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1
Apparatus for enzymology or microbiology
12
with sterilisation, filtration, or dialysis means
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
M
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1
Apparatus for enzymology or microbiology
34
Measuring or testing with condition measuring or sensing means, e.g. colony counters
Applicants:
SUZHOU BOFU BIOMEDICAL LIMITED [CN/CN]; Building A, Science Park, 36 Hua Da Road, Free Trade Zone, Zhangjiagang Suzhou, Jiangsu 215633, CN
Inventors:
YAN, Jing; CN
CHARMET, Jerome; GB
CHRISTIAN, Bauer Wolfgang-Andreas; CN
YU, Ziyi; CN
YANG, Yang; CN
Agent:
SUZHOU CREATOR PATENT & TRADEMARK AGENCY LTD.; No. 93 Ganjiang West Road Suzhou, Jiangsu 215002, CN
Priority Data:
Title (EN) FUNCTIONALIZED MESH AND FLUIDIC APPARATUS FOR CAPTURING CELLS OR MOLECULES IN SOLUTION
(FR) MAILLE FONCTIONNALISÉE ET APPAREIL FLUIDIQUE POUR CAPTURER DES CELLULES OU DES MOLÉCULES EN SOLUTION
Abstract:
(EN) Disclosed are afunctionalized mesh andfluidic apparatusfor capturing cells or molecules in solution. The functionalized mesh comprises a mesh substrate and a functional layer formed on said mesh substrate, wherein the functional layer comprises capturing substances that can specifically bind with the target cells or molecules. The mesh and apparatus of the invention have high specificity, as well as high throughput, and are suitable for capturing molecules in solution or expressed at the surface of cell membranes. It is particularly suited to capture and sort circulating tumor cells.
(FR) L'invention concerne une maille fonctionnalisée et un appareil fluidique pour capturer des cellules ou des molécules en solution. La maille fonctionnalisée comprend un substrat maillé et une couche fonctionnelle formée sur ledit substrat maillé, la couche fonctionnelle comprenant des substances de capture qui peuvent se lier de manière spécifique aux cellules ou molécules cibles. La maille et l'appareil de l'invention ont une spécificité élevée, ainsi qu'un débit élevé, et sont appropriés pour capturer des molécules en solution ou exprimées à la surface de membranes cellulaires. L'invention est particulièrement appropriée pour capturer et trier des cellules tumorales circulantes.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)