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1. (WO2019023873) NANO-LIPID MICROPARTICLE COMPOSITION AND PHARMACEUTICAL COMPOSITION FOR TREATING HEMATOPOIETIC SYSTEM PROLIFERATIVE DISEASES
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Pub. No.: WO/2019/023873 International Application No.: PCT/CN2017/095241
Publication Date: 07.02.2019 International Filing Date: 31.07.2017
IPC:
A61K 31/7068 (2006.01) ,A61K 9/50 (2006.01) ,A61P 35/00 (2006.01) ,A61P 35/02 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7042
Compounds having saccharide radicals and heterocyclic rings
7052
having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
706
containing six-membered rings with nitrogen as a ring hetero atom
7064
containing condensed or non-condensed pyrimidines
7068
having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
48
Preparations in capsules, e.g. of gelatin, of chocolate
50
Microcapsules
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
02
specific for leukemia
Applicants:
江苏竞诺择生物医药科技有限公司 JIANGSU GENALZA BIOPHARMA CO., LTD. [CN/CN]; 中国江苏省南通市 如东县掘港街道珠江路888号高新区生命健康产业园 Life and Health Industry Park of High-Tech Zone, No.888 Zhujiang Street, Juegang Road, Rudong County Nantong, Jiangsu 226400, CN
Inventors:
冯皓 FENG, Hao; CN
Agent:
北京永新同创知识产权代理有限公司 NTD UNIVATION INTELLECTUAL PROPERTY AGENCY LTD.; 中国北京市 西城区金融大街27号投资广场A座1802 Room 1802, Block A, Investment Plaza, 27 Jinrongdajie, Xicheng District Beijing 100033, CN
Priority Data:
Title (EN) NANO-LIPID MICROPARTICLE COMPOSITION AND PHARMACEUTICAL COMPOSITION FOR TREATING HEMATOPOIETIC SYSTEM PROLIFERATIVE DISEASES
(FR) COMPOSITION DE MICROPARTICULES NANO-LIPIDIQUES ET COMPOSITION PHARMACEUTIQUE POUR LE TRAITEMENT DE MALADIES PROLIFÉRATIVES DU SYSTÈME HÉMATOPOÏÉTIQUE
(ZH) 一种用于治疗造血系统增殖性疾病的纳米脂质微粒组合物及药用组合物
Abstract:
(EN) A nano-lipid microparticle composition, the nano-lipid microparticle composition consisting of cytarabine, an anthracycline antibiotic, and a nano-lipid microparticle, wherein the cytarabine and the anthracycline antibiotic are co-encapsulated in the nano-lipid microparticle, and the nano-lipid microparticle comprises a charged lipid stabilizer, the effective average particle size thereof being less than 400 nm.
(FR) L’invention concerne une composition de microparticules nano-lipidiques, la composition de microparticules nano- lipidiques étant constituée de cytarabine, d'un antibiotique de type anthracycline et d'une microparticule nano-lipidique, la cytarabine et l'antibiotique de type anthracycline étant co-encapsulés dans la microparticule nano-lipidique, et la microparticule nano-lipidique comprenant un stabilisant de lipide chargé, dont la taille moyenne de particule efficace est inférieure à 400 nm.
(ZH) 一种纳米脂质微粒组合物,所述纳米脂质微粒组合物由阿糖胞苷、蒽环类抗生素和纳米脂质微粒组成,其中阿糖胞苷和蒽环类抗生素被共包封于纳米脂质微粒中,纳米脂质微粒包含一种带电荷的脂质稳定剂,其有效平均粒径小于400nm。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)