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1. (WO2019023787) SYSTEM, APPARATUS AND METHOD FOR PRODUCING GALLIUM RADIOISOTOPES ON PARTICLE ACCELERATORS USING SOLID TARGETS AND GA-68 COMPOSITION PRODUCED BY SAME
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Pub. No.: WO/2019/023787 International Application No.: PCT/CA2018/000146
Publication Date: 07.02.2019 International Filing Date: 30.07.2018
IPC:
H05H 6/00 (2006.01) ,G21G 1/10 (2006.01) ,A61K 51/02 (2006.01)
H ELECTRICITY
05
ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
H
PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY- CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
6
Targets for producing nuclear reactions
G PHYSICS
21
NUCLEAR PHYSICS; NUCLEAR ENGINEERING
G
CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
1
Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes
04
outside of nuclear reactors or particle accelerators
10
by bombardment with electrically-charged particles
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
51
Preparations containing radioactive substances for use in therapy or testing in vivo
02
characterised by the carrier
Applicants:
ZEISLER, Stefan [CA/CA]; CA
KUMLIN, Joel, Oscar, Olsson [CA/CA]; CA
Inventors:
ZEISLER, Stefan; CA
KUMLIN, Joel, Oscar, Olsson; CA
Agent:
URBANEK, Ted, B.; Urbanek Intellectual Property Law 2300 - 1066 West Hastings Street Vancouver, British Columbia V6E 3X2, CA
Priority Data:
62/538,95431.07.2017US
Title (EN) SYSTEM, APPARATUS AND METHOD FOR PRODUCING GALLIUM RADIOISOTOPES ON PARTICLE ACCELERATORS USING SOLID TARGETS AND GA-68 COMPOSITION PRODUCED BY SAME
(FR) SYSTÈME, APPAREIL ET PROCÉDÉ DE PRODUCTION DE RADIO-ISOTOPES DE GALLIUM SUR DES ACCÉLÉRATEURS DE PARTICULES AU MOYEN DE CIBLES SOLIDES ET COMPOSITION DE GA-68 PRODUITE SELON LE PROCÉDÉ
Abstract:
(EN) The present invention is directed to a system, apparatus, and method for producing gallium radioisotopes on particle accelerators using solid targets and a Ga-68 composition produced by this method. The solid target assembly apparatus has a metal disc and a zinc portion on the top of the disc. The apparatus is made by preparing a quantity of zinc, depositing it onto a metal disc, melting the zinc, and allowing it to cool and solidify. The disc surface may be prepared before applying zinc to it in order to facilitate bonding between the substrate and the zinc. Ga-68 is produced by placing the apparatus in a cyclotron target irradiation station, irradiating it, separating it from the irradiated Zn, and collecting and storing the separated Ga-68. The Ga-68 composition has the following quotient of activity quantity ratios: Ga-67/Ga-68 less than 1, and Ga-67/Ga-68 less than 1.
(FR) La présente invention se rapporte à un système, un appareil, et un procédé de production radio-isotopes de gallium sur des accélérateurs de particules au moyen de cibles solides et une composition de Ga-68 produite selon ce procédé. L'appareil de montage de cibles solides a un disque de métal et une partie en zinc sur le dessus du disque. L'appareil est réalisé en préparant une quantité de zinc, en la déposant sur un disque de métal, en faisant fondre le zinc et en le laissant refroidir et solidifier. La surface du disque peut être préparée avant d'y appliquer le zinc afin de faciliter la liaison entre le substrat et le zinc. Du Ga-68 est produit en plaçant l'appareil dans une station d'irradiation de cible de cyclotron, en l'irradiant, en le séparant du Zn irradié, et en collectant et en conservant le Ga-68 séparé. La composition de Ga-68 a le quotient de ratios de quantité d'activité suivant : Ga-67/Ga-68 inférieur à 1, et Ga-67/Ga-68 inférieur à 1.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)