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1. (WO2019023764) DEVICE FOR DETECTING THE ADAM10 BIOMARKER FOR THE DIAGNOSIS OF ALZHEIMER'S DISEASE, METHOD FOR THE APPLICATION OF SAID DEVICE, USE OF SAID DEVICE FOR THE DIAGNOSIS OF ALZHEIMER'S DISEASE, AND ELISA APPLICATION METHOD FOR THE DIAGNOSIS OF ALZHEIMER'S DISEASE
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Pub. No.: WO/2019/023764 International Application No.: PCT/BR2017/000086
Publication Date: 07.02.2019 International Filing Date: 04.08.2017
IPC:
G01N 33/541 (2006.01) ,G01N 33/551 (2006.01) ,G01N 33/535 (2006.01) ,G01N 27/327 (2006.01) ,C07K 14/47 (2006.01) ,H05K 3/12 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
536
with immune complex formed in liquid phase
537
with separation of immune complex from unbound antigen or antibody
539
involving precipitating reagent
541
Double or second antibody
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
543
with an insoluble carrier for immobilising immunochemicals
551
the carrier being inorganic
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
531
Production of immunochemical test materials
532
Production of labelled immunochemicals
535
with enzyme label
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27
Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
26
by investigating electrochemical variables; by using electrolysis or electrophoresis
28
Electrolytic cell components
30
Electrodes, e.g. test electrodes; Half-cells
327
Biochemical electrodes
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
46
from vertebrates
47
from mammals
H ELECTRICITY
05
ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
K
PRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
3
Apparatus or processes for manufacturing printed circuits
10
in which conductive material is applied to the insulating support in such a manner as to form the desired conductive pattern
12
using printing techniques to apply the conductive material
Applicants:
FUNDAÇÃO UNIVERSIDADE FEDERAL DE SÃO CARLOS [BR/BR]; CNPJ/CPF: 45.358.058/0001-40 Endereço: Rodovia Washington Luis, Km 235 Caixa Postal 147 13565-905 São Carlos - SP, BR
Inventors:
CENSI FARIA, Ronaldo; BR
DE OLIVEIRA, Tassia Regina; BR
ERBERELI, Camila Regina; BR
MANZINE MORALLES, Patricia Regina; BR
COMINETTI, Marcia Regina; BR
Agent:
DE MORAES, Daniel Roza; CPF: 309.842.818-00 / OAB: 277.727 Endereço: Rodovia Washington Luis, Km 235 Caixa Postal 147 13565-905 São Carlos - SP, BR
Priority Data:
BR 10 2016 018150-004.08.2017BR
Title (EN) DEVICE FOR DETECTING THE ADAM10 BIOMARKER FOR THE DIAGNOSIS OF ALZHEIMER'S DISEASE, METHOD FOR THE APPLICATION OF SAID DEVICE, USE OF SAID DEVICE FOR THE DIAGNOSIS OF ALZHEIMER'S DISEASE, AND ELISA APPLICATION METHOD FOR THE DIAGNOSIS OF ALZHEIMER'S DISEASE
(FR) DISPOSITIF POUR LA DÉTECTION DU BIOMARQUEUR ADAM10 POUR LE DIAGNOSTIC DE LA MALADIE D'ALZHEIMER, MÉTHODE D'APPLICATION DUDIT DISPOSITIF, UTILISATION DUDIT DISPOSITIF POUR LE DIAGNOSTIC DE LA MALADIE D'ALZHEIMER, MÉTHODE D'APPLICATION D'ELISA POUR LE DIAGNOSTIC DE LA MALADIE D'ALZHEIMER
(PT) DISPOSITIVO PARA DETECÇÃO DO BIOMARCADOR ADAMI 0 PARA O DIAGNOSTICO DA DOENÇA DE ALZHEIMER, MÉTODO DE APLICAÇÃO DO REFERIDO DISPOSITIVO, USO DO DITO DISPOSITIVO PARA DIAGNÓSTICO DA DOEMÇA DE ALZHEIMER, MÉTODO DE APLICAÇÃO DE ELISA PARA DIAGNÓSTICO DA DOENÇA DE ALZHEIMER
Abstract:
(EN) The present invention relates to a device for detecting the ADAM10 biomarker for the diagnosis of Alzheimer's disease, preferably being disposable immunosensors, which offers a number of advantages when compared with other devices for the same purpose, including a high level of sensitivity, being furthermore capable of indicating different stages of the disease. The present invention also relates to methods of application of said device and the use thereof for the diagnosis of Alzheimer's disease. In addition, the present invention relates to the method of application of the ELISA procedure for the diagnosis of Alzheimer's disease.
(FR) La présente invention concerne un dispositif pour la détection du biomarqueur ADAM10 pour le diagnostic de la maladie d'Alzheimer, de préférence sous la forme d'immunocapteurs jetables, présentant divers avantages par comparaison avec d'autres dispositifs ayant la même vocation, notamment une haute sensibilité, et permettant en outre d'indiquer différents stades de la maladie. La présente invention concerne également des méthodes d'application dudit dispositif et son utilisation pour le diagnostic de la maladie d'Alzheimer. La présente invention se rapporte en outre à une méthode d'application du procédé ELISA pour le diagnostic de la maladie d'Alzheimer.
(PT) A presente invenção refere-se a um dispositivo para detecção do biomarcador ADAM 10 para diagnóstico da Doença de Alzheimer sendo preferencialmente imunossensores descartáveis que apresenta diversas vantagens quando comparado com outros dispositivos para o mesmo propósito incluindo aita sensibilidade, sendo capaz ainda de indicar diferentes estágios da doença. Ainda, a presente invenção refere-se a métodos de aplicação do referido dispositivo e uso deste para diagnóstico da Doença de Aizheímer. E a presente invenção refere-se ainda a método de aplicação do procedimento ELISA para diagnóstico da Doença de Alzheimer.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Portuguese (PT)
Filing Language: Portuguese (PT)