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1. (WO2019023741) TREATMENT OF STAPHYLOCOCCAL AND ENTEROCOCCAL INFECTIONS USING SUBSTITUTED NITROSTYRENE COMPOUNDS
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Pub. No.: WO/2019/023741 International Application No.: PCT/AU2018/050788
Publication Date: 07.02.2019 International Filing Date: 30.07.2018
IPC:
A61K 31/36 (2006.01) ,A61K 31/4184 (2006.01) ,A61K 31/423 (2006.01) ,A61K 38/14 (2006.01) ,A61P 31/04 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
357
having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
36
Compounds containing methylenedioxyphenyl groups, e.g. sesamin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
4164
1,3-Diazoles
4184
condensed with carbocyclic rings, e.g. benzimidazoles
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
42
Oxazoles
423
condensed with carbocyclic rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
04
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
14
Peptides containing saccharide radicals; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04
Antibacterial agents
Applicants:
OPAL BIOSCIENCES LIMITED [AU/AU]; Level 4, 100 Albert Road South Melbourne, Victoria 3025, AU
Inventors:
JENSEN, Slade; AU
RADZIETA, Michael; AU
Agent:
DAVIES COLLISON CAVE PTY LTD; 1 Nicholson Street Melbourne, Victoria 3000, AU
Priority Data:
201790303301.08.2017AU
Title (EN) TREATMENT OF STAPHYLOCOCCAL AND ENTEROCOCCAL INFECTIONS USING SUBSTITUTED NITROSTYRENE COMPOUNDS
(FR) TRAITEMENT D'INFECTIONS À STAPHYLOCOQUES ET À ENTÉROCOQUES À L'AIDE DE COMPOSÉS DE NITROSTYRÈNE SUBSTITUÉS
Abstract:
(EN) The invention relates generally to the use of substituted nitrostyrene compounds in the treatment of Staphylococcus aureus and Enterococcal infections. In particular aspects the present invention relates to the use of these compounds in the treatment S. aureus infections where the bacteria have a level of vancomycin resistance.
(FR) L'invention concerne de manière générale l'utilisation de composés de nitrostyrène substitués dans le traitement d'infections par Staphylococcus aureus et Entérocoques. Dans des aspects particuliers, la présente invention concerne l'utilisation de ces composés dans le traitement d'infections par S. aureus où les bactéries ont un niveau de résistance à la vancomycine.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)