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1. (WO2019009577) PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD THEREFOR
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Pub. No.: WO/2019/009577 International Application No.: PCT/KR2018/007488
Publication Date: 10.01.2019 International Filing Date: 02.07.2018
IPC:
A61K 9/50 (2006.01) ,A61K 38/43 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
48
Preparations in capsules, e.g. of gelatin, of chocolate
50
Microcapsules
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
43
Enzymes; Proenzymes; Derivatives thereof
Applicants:
남봉길 NAM, Bong Gil [KR/KR]; KR
주식회사 한국팜비오 PHARMBIO KOREA CO., LTD. [KR/KR]; 충청북도 충주시 대소원면 첨단산업9로 36 36, Cheomdansaneop 9-ro, Daesowon-myeon, Chungju-si Chungcheongbuk-do 27466, KR
Inventors:
남봉길 NAM, Bong Gil; KR
이병준 LEE, Byeung Jun; KR
진순지 JIN, Shun ji; KR
Agent:
특허법인 가산 KASAN IP & LAW FIRM; 서울시 서초구 남부순환로 2423, 한원빌딩 7층 7th Floor, HanwonBuilding, 2423 Nambusunhwan-ro Seocho-gu Seoul 06719, KR
Priority Data:
10-2017-008434603.07.2017KR
Title (EN) PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD THEREFOR
(FR) COMPOSITION PHARMACEUTIQUE ET PROCÉDÉ DE PRÉPARATION ASSOCIÉ
(KO) 약제학적 조성물 및 그 제조 방법
Abstract:
(EN) A pharmaceutical composition for removing gastric mucus, and a preparation method therefor are provided. The pharmaceutical composition comprises core particles comprising pronase B, a first excipient, and a first binder, and comprises a plurality of coating particles comprising a first coating layer formed on at least one portion of the core particles, wherein the diameter of 80% or more of the total coating particles is 180-500 μm.
(FR) L'invention concerne une composition pharmaceutique pour retirer le mucus gastrique et un procédé de préparation associé. La composition pharmaceutique comprend des particules de cœur comprenant de la prononase B, un premier excipient et un premier liant, et comprend une pluralité de particules de revêtement comprenant une première couche de revêtement formée sur au moins une partie des particules de cœur, le diamètre de 80 % ou plus des particules de revêtement totales étant compris entre 180 et 500 µm.
(KO) 위 점액 제거용 약제학적 조성물 및 그 제조방법이 제공된다. 약제학적 조성물은 프로나제 B를 포함하는 코어 입자 및 제1 부형제 및 제1 결합제를 포함하며 상기 코어 입자 상의 적어도 일부분에 형성되는 제1 코팅층을 포함하는 코팅 입자를 복수 개 포함하고, 전체 상기 코팅 입자의 80% 이상은 입경이 180~500㎛이다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)