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1. (WO2019009346) ANTI-HUMAN IGG4 MONOCLONAL ANTIBODY AND HUMAN IGG4 ASSAY REAGENT USING SAID ANTIBODY
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Pub. No.: WO/2019/009346 International Application No.: PCT/JP2018/025441
Publication Date: 10.01.2019 International Filing Date: 05.07.2018
IPC:
C12N 15/13 (2006.01) ,C07K 16/42 (2006.01) ,C12N 5/20 (2006.01) ,G01N 33/53 (2006.01) ,G01N 33/543 (2006.01) ,G01N 33/544 (2006.01) ,C12P 21/08 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
12
Genes encoding animal proteins
13
Immunoglobulins
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
42
against immunoglobulins (anti-idiotypic antibodies)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
10
Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
12
Fused cells, e.g. hybridomas
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Animal cells
18
Murine cells, e.g. mouse cells
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one of the fusion partners being a B lymphocyte
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
543
with an insoluble carrier for immobilising immunochemicals
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
543
with an insoluble carrier for immobilising immunochemicals
544
the carrier being organic
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
21
Preparation of peptides or proteins
08
Monoclonal antibodies
Applicants:
日東紡績株式会社 NITTO BOSEKI CO., LTD. [JP/JP]; 福島県福島市郷野目字東1番地 1, Aza Higashi, Gonome, Fukushima-shi, Fukushima 9608161, JP
Inventors:
照内 友也 TERUUCHI Yuya; JP
松木 友里 MATSUKI Yuri; JP
稲垣 量光 INAGAKI Kazumitsu; JP
佐々木 大介 SASAKI Daisuke; JP
柏倉 春香 KASHIWAGURA Haruka; JP
Agent:
特許業務法人浅村特許事務所 ASAMURA PATENT OFFICE, P.C.; 東京都品川区東品川2丁目2番24号 天王洲セントラルタワー Tennoz Central Tower, 2-2-24 Higashi-Shinagawa, Shinagawa-ku, Tokyo 1408776, JP
Priority Data:
2017-13284106.07.2017JP
Title (EN) ANTI-HUMAN IGG4 MONOCLONAL ANTIBODY AND HUMAN IGG4 ASSAY REAGENT USING SAID ANTIBODY
(FR) ANTICORPS MONOCLONAL ANTI-IGG4 HUMAINE ET RÉACTIF DE DOSAGE D'IGG4 HUMAINE L'UTILISANT
(JA) 抗ヒトIgG4モノクローナル抗体、およびその抗体を利用したヒトIgG4測定試薬
Abstract:
(EN) Provided are: a monoclonal antibody against human IgG4, for which the epitope is present in the CH3 of human IgG4 given by SEQ ID NO: 4; a hybridoma that produces the monoclonal antibody; a method for detecting IgG4 using the monoclonal antibody; and a kit used in this method.
(FR) L'invention concerne : un anticorps monoclonal anti-IgG4 humaine, pour lequel l'épitope est présent dans le CH3 d'une IgG4 humaine donné par SEQ ID No : 4 ; un hybridome qui produit l'anticorps monoclonal ; un procédé de détection de l'IgG4 à l'aide de l'anticorps monoclonal ; et un kit utilisé dans ce procédé.
(JA) エピトープが、配列番号4に示すヒトIgG4のCH3に存在する、ヒトIgG4に対するモノクローナル抗体、それを産生するハイブリドーマ、該モノクローナル抗体を用いたIgG4の検出方法およびそれに使用するキットを提供する。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)