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1. (WO2019007999) PROTECTED TETRASACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE AS TRANSGLUCOSYLASE ACCEPTOR SUBSTRATES IN THE CHEMO-ENZYMATIC SYNTHESIS OF SHIGELLA FLEXNERI SPECIFIC OLIGOSACCHARIDES
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Pub. No.: WO/2019/007999 International Application No.: PCT/EP2018/068013
Publication Date: 10.01.2019 International Filing Date: 03.07.2018
IPC:
C07H 15/00 (2006.01) ,C07H 15/10 (2006.01) ,C12P 19/12 (2006.01) ,C12P 19/26 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
H
SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
15
Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
H
SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
15
Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
02
Acyclic radicals, not substituted by cyclic structures
04
attached to an oxygen atom of a saccharide radical
10
containing unsaturated carbon-to-carbon bonds
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19
Preparation of compounds containing saccharide radicals
12
Disaccharides
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19
Preparation of compounds containing saccharide radicals
26
Preparation of nitrogen-containing carbohydrates
Applicants:
INSTITUT PASTEUR [FR/FR]; 28 rue du Docteur Roux 75015 Paris, FR
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE [FR/FR]; 147 rue de l'Université 75007 Paris, FR
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE [FR/FR]; 135 avenue de Rangueil 31077 Toulouse Cedex 4, FR
UNIVERSITE PARIS 13 PARIS NORD [FR/FR]; 99, avenue Jean-Baptiste Clément 93430 Villetaneuse, FR
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE [FR/FR]; 3, rue Michel Ange 75016 Paris, FR
Inventors:
MULARD, Laurence; FR
LE HEIGET, Guillaume; FR
HU, Zhaohu; CN
BAREL, Louis-Antoine; FR
ANDRE, Isabelle; FR
MOULIS, Claire; FR
REMAUD-SIMEON, Magali; FR
BARBE, Sophie; FR
BENKOULOUCHE, Mounir; FR
BEN IMEDDOURENE, Akli; FR
Agent:
GEVERS & ORES; 41, avenue de Friedland 75008 PARIS, FR
Priority Data:
62/528,27703.07.2017US
Title (EN) PROTECTED TETRASACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE AS TRANSGLUCOSYLASE ACCEPTOR SUBSTRATES IN THE CHEMO-ENZYMATIC SYNTHESIS OF SHIGELLA FLEXNERI SPECIFIC OLIGOSACCHARIDES
(FR) TÉTRAHOLOSIDES PROTÉGÉS, LEUR PROCÉDÉ DE PRÉPARATION ET LEUR UTILISATION EN TANT QUE SUBSTRATS ACCEPTEURS DE TRANSGLUCOSYLASE DANS LA SYNTHÈSE CHIMIO-ENZYMATIQUE D'OLIGOSACCHARIDES SHIGELLA FLEXNERI SPÉCIFIQUES
Abstract:
(EN) The present invention provides protected tetrasaccharides, their process of preparation and their use in the synthesis of oligosaccharides, in particular fragments of O-antigens from Shigella flexneri, for example of serotype la, lb, 2a, 2b, 3a, X, 4a, 4b, 5a, 5b, 7a or 7b.
(FR) La présente invention concerne des tétraholosides protégés, leur procédé de préparation et leur utilisation dans la synthèse d'oligosaccharides, en particulier des fragments d'antigènes O de Shigella flexneri, par exemple du sérotype la, lb, 2a, 2b, 3a, X, 4a, 4b, 5a, 5b, 7a ou 7b.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)