Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2019007415) FURAN-NAPHTHOQUINONE-BASED SULFOXIMINE DERIVATIVE AND USE OF SAME IN PREPARATION OF STAT3 INHIBITOR
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2019/007415 International Application No.: PCT/CN2018/094781
Publication Date: 10.01.2019 International Filing Date: 06.07.2018
IPC:
C07D 307/92 (2006.01) ,A61K 31/343 (2006.01) ,A61P 35/00 (2006.01) ,A61P 35/04 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
307
Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
77
ortho- or peri-condensed with carbocyclic rings or ring systems
92
Naphthofurans; Hydrogenated naphthofurans
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
34
having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
343
condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
04
specific for metastasis
Applicants:
北京大学 PEKING UNIVERSITY [CN/CN]; 中国北京市 海淀区学院路38号 No. 38, Xueyuan Road, Haidian District Beijing 100191, CN
Inventors:
李润涛 LI, Runtao; CN
李润润 LI, Runrun; CN
葛泽梅 GE, Zemei; CN
王欣 WANG, Xin; CN
程铁明 CHENG, Tieming; CN
Agent:
北京信慧永光知识产权代理有限责任公司 BEIJING SUNHOPE INTELLECTUAL PROPERTY LTD.; 中国北京市 海淀区知春路9号坤讯大厦1106室 Suite 1106, Kunxun Plaza, Zhichun Road 9 Haidian District Beijing 100191, CN
Priority Data:
201710545554.306.07.2017CN
Title (EN) FURAN-NAPHTHOQUINONE-BASED SULFOXIMINE DERIVATIVE AND USE OF SAME IN PREPARATION OF STAT3 INHIBITOR
(FR) DÉRIVÉ DE SULFOXIMINE À BASE DE FURANE-NAPHTOQUINONE ET SON UTILISATION DANS LA PRÉPARATION D'UN INHIBITEUR DE STAT3
(ZH) 基于呋喃萘醌的亚砜亚胺衍生物及其在制造STAT3抑制剂中的用途
Abstract:
(EN) Disclosed are a furan-naphthoquinone-based sulfoximine derivative as shown in formula (I), a pharmaceutical composition containing the derivative and the use of the derivative as an STAT3 inhibitor.
(FR) L'invention concerne un dérivé de sulfoximine à base de furane-naphtoquinone tel que représenté par la formule (I), une composition pharmaceutique contenant le dérivé et l'utilisation du dérivé en tant qu'inhibiteur de STAT3.
(ZH) 式(I)所示的基于呋喃萘醌的亚砜亚胺衍生物、包含该衍生物的药物组合物以及该衍生物作为STAT3抑制剂的用途。
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)