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1. (WO2019006534) PROBIOTIC-BASED TREATMENT OF RESISTANT CHRONIC RHINOSINUSITIS
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Pub. No.: WO/2019/006534 International Application No.: PCT/CA2017/050814
Publication Date: 10.01.2019 International Filing Date: 06.07.2017
IPC:
A61K 35/741 (2015.01) ,A61K 31/58 (2006.01) ,A61K 35/744 (2015.01) ,A61P 11/02 (2006.01) ,C07J 71/00 (2006.01) ,C12N 1/20 (2006.01)
[IPC code unknown for A61K 35/741]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
56
Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
58
containing heterocyclic rings, e.g. aldosterone, danazol, stanozolol, pancuronium, digitogenin
[IPC code unknown for A61K 35/744]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
02
Nasal agents, e.g. decongestants
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
J
STEROIDS
71
Steroids in which the cyclopenta[a]hydrophenanthrene skeleton is condensed with a heterocyclic ring
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1
Micro-organisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving micro-organisms or compositions thereof; Processes of preparing or isolating a composition containing a micro-organism; Culture media therefor
20
Bacteria; Culture media therefor
Applicants:
PROBIONASE THERAPIES INC. [CA/CA]; 1151, Boulevard du Mont-Royal Outremont, Québec H2V 2H6, CA
Inventors:
DESROSIERS, Martin; CA
Agent:
LAVERY, DE BILLY, LLP; 1 Place Ville Marie, Suite 4000 Montréal, Québec H3B 4M4, CA
Priority Data:
Title (EN) PROBIOTIC-BASED TREATMENT OF RESISTANT CHRONIC RHINOSINUSITIS
(FR) TRAITEMENT À BASE DE PROBIOTIQUES CONTRE UNE RHINOSINUSITE CHRONIQUE RÉSISTANTE
Abstract:
(EN) Methods, uses, compositions and kits for treating steroid-resistant chronic rhinosinusitis (CRS), including refractory CRS, in a subject, or for improving or restoring the response to anti- inflammatory sinus treatment in a patient suffering from steroid-resistant CRS, are described. These methods, uses, compositions and kits are based on the sinus administration of an effective amount of probiotics, such as lactic acid bacteria (LAB), for example lactococcus lactis bacteria.
(FR) L'invention concerne des méthodes, des utilisations, des compositions et des kits pour le traitement d'une rhinosinusite chronique résistant aux stéroïdes, dont une rhinosinusite chronique réfractaire, chez un sujet, ou pour améliorer ou restaurer la réponse à un traitement anti-inflammatoire au niveau des sinus chez un patient souffrant d'une rhinosinusite chronique résistant aux stéroïdes. Ces méthodes, utilisations, compositions et kits sont basés sur l'administration au niveau des sinus d'une quantité efficace de probiotiques, tels que des bactéries lactiques, par exemple des bactéries de type Lactococcus lactis.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)