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1. (WO2019005955) IMPROVED REVERSE TRANSCRIPTASE AND METHODS OF USE
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Pub. No.: WO/2019/005955 International Application No.: PCT/US2018/039738
Publication Date: 03.01.2019 International Filing Date: 27.06.2018
IPC:
C12N 9/22 (2006.01) ,C07K 14/00 (2006.01) ,C07K 14/195 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9
Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
14
Hydrolases (3.)
16
acting on ester bonds (3.1)
22
Ribonucleases
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195
from bacteria
Applicants:
YALE UNIVERSITY [US/US]; Two Whitney Avenue New Haven, CT 06510, US
Inventors:
PYLE, Anna Marie; US
ZHAO, Chen; US
Agent:
FONVILLE, Natalie; US
CAMPBELL, Christopher; US
CHEN, Ming; US
ALLEN, Justin; US
ARTIS, Ryan; US
Priority Data:
62/525,33727.06.2017US
Title (EN) IMPROVED REVERSE TRANSCRIPTASE AND METHODS OF USE
(FR) TRANSCRIPTASE INVERSE AMÉLIORÉE ET PROCÉDÉS D'UTILISATION ASSOCIÉS
Abstract:
(EN) The present disclosure provides compositions, methods, and kits related to enhanced reverse transcriptases comprising Eubacterium rectale maturase having one or more mutations.
(FR) La présente invention concerne des compositions, des procédés et des kits associés à des transcriptases inverses améliorées comprenant une maturase d'Eubacterium rectale ayant une ou plusieurs mutations.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)