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1. (WO2019005636) ANTI-ROR1 ANTIBODIES AND METHODS OF MAKING AND USING THEREOF
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Pub. No.: WO/2019/005636 International Application No.: PCT/US2018/039152
Publication Date: 03.01.2019 International Filing Date: 22.06.2018
IPC:
C12Q 1/68 (2018.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
Applicants:
SYSTIMMUNE, INC. [US/US]; 15318 NE 95th St Redmond, WI 98052, US
SICHUAN BAILI PHARMACEUTICAL CO. LTD. [CN/CN]; 161 Baili Road, Wenjiang District Chengdu, Sichuan, CN
Inventors:
OLSEN, Ole; US
TAN, Phil; US
XIA, Dong; US
JELLYMAN, David; US
KOVACEVICH, Brian; US
BRADY, Bill; US
RENSHAW, Blair; US
GAO, Zeren; US
ZHU, Yi; CN
Agent:
HAN, Zhihua; US
Priority Data:
62/524,55425.06.2017US
62/524,55725.06.2017US
62/524,55825.06.2017US
62/545,60315.08.2017US
62/551,03228.08.2017US
62/551,03528.08.2017US
62/551,06528.08.2017US
Title (EN) ANTI-ROR1 ANTIBODIES AND METHODS OF MAKING AND USING THEREOF
(FR) ANTICORPS ANTI-ROR1 ET LEURS PROCÉDÉS DE PRÉPARATION ET D'UTILISATION
Abstract:
(EN) The application provides anti-ROR1 monoclonal antibodies, antigen binding portions thereof, therapeutic compositions thereof and/or nucleic acid encoding the same, and their use to upregulate the function of T-cells to enhance cell-mediated immune responses in the treatment of cancer and other T-cell dysfunctional disorders.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)