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1. (WO2019004738) USE OF COMPOSITION COMPRISING ADIPOSE STEM CELL-DERIVED EXOSOME AS EFFECTIVE INGREDIENT IN ALLEVIATING DERMATITIS
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Pub. No.: WO/2019/004738 International Application No.: PCT/KR2018/007326
Publication Date: 03.01.2019 International Filing Date: 28.06.2018
IPC:
A61K 35/28 (2015.01) ,A23L 33/10 (2016.01) ,A61K 8/98 (2006.01) ,A61Q 19/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
12
Materials from mammals or birds
28
Marrow; Spleen
[IPC code unknown for A23L 33/10]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
18
characterised by the composition
96
containing materials, or derivatives thereof, of undetermined constitution
98
of animal origin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
Q
SPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19
Preparations for care of the skin
Applicants:
주식회사 엑소코바이오 EXOCOBIO INC. [KR/KR]; 서울시 금천구 가산디지털1로 19, 306호 Suite 306, 19, Gasan digital 1-ro Geumcheon-gu Seoul 08594, KR
Inventors:
이용원 YI, Yong Weon; KR
조병성 CHO, Byong Seung; KR
Agent:
이동기 LEE, Dong-Ki; KR
Priority Data:
10-2017-008350630.06.2017KR
10-2017-011117931.08.2017KR
10-2018-001861714.02.2018KR
10-2018-006285431.05.2018KR
Title (EN) USE OF COMPOSITION COMPRISING ADIPOSE STEM CELL-DERIVED EXOSOME AS EFFECTIVE INGREDIENT IN ALLEVIATING DERMATITIS
(FR) UTILISATION D'UNE COMPOSITION COMPRENANT UN EXOSOME DÉRIVÉ DE CELLULES SOUCHES ADIPEUSES EN TANT QUE PRINCIPE ACTIF POUR ATTÉNUER LA DERMATITE
(KO) 지방줄기세포 유래의 엑소좀을 유효성분으로 포함하는 조성물의 피부염 개선 용도
Abstract:
(EN) The present invention provides a composition comprising adipose stem cell-derived exosomes as an effective ingredient for preventing, alleviating, reducing, or treating dermatitis. Acting on multiple cytokine targets causative of dermatitis, a composition according to the present invention can be applied to a wide spectrum of dermatitis attributed to various causes and can effectively suppress or reduce dermatitis. In addition, the composition of the present invention can reduce moisture evaporation of the stratum corneum and improve skin moisturization to protect and reinforce skin barriers whereby dermatitis can be prevented, alleviated, reduced, or treated.
(FR) La présente invention concerne une composition contenant comme principe actif des exosomes dérivés de cellules souches adipeuses humaines pour prévenir, atténuer ou traiter la dermatite. Agissant sur de multiples cibles de cytokine à l'origine de la dermatite, une composition selon la présente invention peut être appliquée à un large spectre de dermatites attribuées à diverses causes et peut supprimer ou réduire efficacement la dermatite. De plus, la composition de la présente invention peut réduire l'évaporation de l'humidité de la couche cornée et améliorer l'hydratation de la peau pour protéger et renforcer les barrières cutanées, la dermatite pouvant ainsi être évitée, atténuée, réduite ou traitée.
(KO) 본 발명은 지방줄기세포 유래의 엑소좀을 유효성분으로 포함하는, 피부염의 예방, 개선, 완화 또는 치료용 조성물을 제공한다. 본 발명의 조성물은 피부염을 일으키는 다중 사이토카인 표적에 대해 작용하여 다양한 원인에 기인하는 피부염에 대한 광범위한 적용이 가능하고 효과적으로 피부염을 억제 및 완화시킬 수 있다. 또한, 본 발명의 조성물은 각질층의 수분증발을 감소시키고 피부 보습을 향상시켜 피부장벽을 보호 및 강화시킬 수 있고, 이러한 피부장벽 보호 및 강화를 통해 피부염을 예방, 개선, 완화 또는 치료할 수 있다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)