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1. (WO2019004645) BIOSIGNAL MEASURING BIOELECTRODE BASED ON NANOPOROUS PERMEABLE MEMBRANE HAVING HIGH SPECIFIC SURFACE AREA, AND METHOD FOR MANUFACTURING SAME
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Pub. No.: WO/2019/004645 International Application No.: PCT/KR2018/006891
Publication Date: 03.01.2019 International Filing Date: 19.06.2018
IPC:
A61B 5/04 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
04
Measuring bioelectric signals of the body or parts thereof
Applicants:
강원대학교산학협력단 KNU-INDUSTRY COOPERATION FOUNDATION [KR/KR]; 강원도 춘천시 강원대학길 1 1, Gangwondaehak-gil Chuncheon-si Gangwon-do 24341, KR
Inventors:
이광호 LEE, Kwang Ho; KR
김지훈 KIM, Ji Hun; KR
Agent:
김정현 KIM, Jeong Hyeon; KR
Priority Data:
10-2017-008236729.06.2017KR
Title (EN) BIOSIGNAL MEASURING BIOELECTRODE BASED ON NANOPOROUS PERMEABLE MEMBRANE HAVING HIGH SPECIFIC SURFACE AREA, AND METHOD FOR MANUFACTURING SAME
(FR) BIOÉLECTRODE DE MESURE DE BIOSIGNAL BASÉE SUR UNE MEMBRANE PERMÉABLE NANOPOREUSE AYANT UNE SURFACE DE CONTACT SPÉCIFIQUE ÉLEVÉE, ET SON PROCÉDÉ DE FABRICATION
(KO) 높은 비표면적을 가지는 다공성 나노투과막 기반의 생체신호 측정용 생체전극 및 그의 제조방법
Abstract:
(EN) The present invention relates to a bioelectrode having improved conductivity, flexibility, and biocompatibility, and a method for manufacturing the same. Particularly, the present invention relates to a conductive polymer bioelectrode comprising a biocompatible polymer substance-based nanoporous permeable membrane having a plurality of pores and an improved surface area, a biosignal transferring pattern layer, and a gold coating layer, based on a PDMS device having low mechanical strength and excellent biocompatibility, whereby the conductive polymer bioelectrode is similar in conductivity to that of a conventional metallic bioelectrode and shows excellent biocompatibility, with the incurrence of a low rejection response. Therefore, it is expected that the conductive polymer bioelectrode of the present invention can replace a metallic bioelectrode, which has poor biosignal transfer efficiency due to the high bioincompatibility thereof.
(FR) La présente invention concerne une bioélectrode ayant une conductivité, une flexibilité et une biocompatibilité améliorées, et son procédé de fabrication. En particulier, la présente invention concerne une bioélectrode polymère conductrice comprenant une membrane perméable nanoporeuse à base de substance polymère biocompatible ayant une pluralité de pores et une surface de contact améliorée, une couche de motif de transfert de biosignal, et une couche de revêtement d'or, sur la base d'un dispositif PDMS ayant une faible résistance mécanique et une excellente biocompatibilité, moyennant quoi la bioélectrode polymère conductrice est similaire en termes de conductivité à une bioélectrode métallique classique et présente une excellente biocompatibilité, avec la génération d'une réponse à faible rejet. Par conséquent, il est attendu que la bioélectrode polymère conductrice de la présente invention peut remplacer une bioélectrode métallique, qui présente une faible efficacité de transfert de biosignal en raison de sa bioincompatibilité élevée.
(KO) 본 발명은 전도성, 유연성 및 생체적합성이 향상된 생체전극 및 그의 제조방법에 관한 것이다. 상세하게는, 낮은 기계적 강도 및 우수한 생체적합성을 가진 PDMS 디바이스를 기반으로 다수의 공극을 가지며 표면적이 향상된 생체적합성 고분자 물질 기반의 나노다공성 투과막, 생체신호전달용 패터닝 및 금코팅층을 포함하여 종래의 금속소재 생체전극과 유사한 전도도를 가지면서도 생체 적합성이 뛰어나 거부반응이 적은 전도성 고분자 생체전극에 관한 것이다. 따라서 본 발명의 전도성 고분자 생체전극은 높은 생체부적합성으로 인하여 생체신호 전달 효율이 저하되는 금속소재의 생체전극을 대체할 수 있을 것으로 기대된다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)